Results 121 to 130 of about 156,390 (266)
ABSTRACT We introduce RNA‐DNA fusomers, a new class of chemically synthesized oligonucleotides that combine the versatile properties of RNA and DNA within a single sequence and self‐assemble into higher‐order functional structures via a simple one‐pot annealing reaction.
Yasmine Radwan +21 more
wiley +1 more source
Diagram of the genomic context of different lncRNA subtypes.
(a) CI: Completely Intronic lncRNA, IA: Intronic Antisense lncRNA and IO: Intron Overlapping lncRNA; (b) 3UO: 3/UTR Overlapping lncRNA, 5UO: 5/UTR Overlapping lncRNA, CD: CDS overlapping lncRNA and AN: Antisense lncRNA; (c) SO: Sense Overlapping lncRNA; (
Sudipto Saha (64064) +4 more
core +1 more source
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley +1 more source
Validated lncRNA from blood stranded RNA-Seq that overlap with class 3 un-stranded lncRNA.
Validated lncRNA from blood stranded RNA-Seq that overlap with class 3 un-stranded lncRNA.
Christy Vander Jagt (817483) +4 more
core +1 more source
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He +10 more
wiley +1 more source
The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu +6 more
wiley +1 more source
Iflaviruses in arthropods: when small is mighty
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
A 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer
Xuning Wang,1 Jianguo Zhou,2 Maolin Xu,1 Yongfeng Yan,3 Liang Huang,1 Yanshen Kuang,1 Yuansheng Liu,4 Peng Li,3 Wei Zheng,3 Hongyi Liu,3 Baoqing Jia3 1Department of General Surgery, Chinese PLA Medical School, Beijing 100853, People’s Republic of ...
Liu H +10 more
core
TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li +8 more
wiley +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source

