Results 121 to 130 of about 90,265 (219)

Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer

Cancer Science, EarlyView.
Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang, Tianli Zhang, Xue Kong, Yao Tong, Yanru Li, Xiangjun Dong, Chuanxin Wang, Juan Li   +7 more
wiley   +1 more source

Targeting non-canonical antigens unlocks functional T-cell responses in renal cell carcinoma. [PDF]

J Immunother Cancer
Wang J, Zhu Y, He X, Yin S, He Y, Yao P, Li J, Li X, Shi P, Qian R, Xiao Z, Ye X, Xi JJ, Ye B.   +13 more
europepmc   +1 more source

Urinary Small Extracellular Vesicle DNA as a Biomarker for the Non‐Invasive Diagnosis of Bladder Cancer

Cancer Science, EarlyView.
Clinical application scenarios for the diagnosis of BC. A schematic diagram illustrating the use of sEV DNA liquid biopsy technology to differentiate between benign and bladder cancer patients. ABSTRACT Existing diagnostic technologies for bladder cancer (BC) suffer from low sensitivity, low specificity, or a lack of validation.
Tao Wang, Xin Liao, Jiyang Zhang, Xiaoya Xu, Wei Zhang, Xinlin Chen, Xinyu Zhai, Tongtong Zhang, Xiangyang Zhan, Xingyu Mu, Dadong Zhang, Jian Chen, Dongliang Xu, Mingyue Tan   +13 more
wiley   +1 more source

Correlations of m6A Methylation-Related lncRNAs with the Prognosis of Papillary Thyroid Carcinoma

International Journal of General Medicine
Xiang Li,1 Zigang Ding,1 Yun Tong2 1Department of General Surgery, The Affiliated Hospital of Jiujiang University, Jiujiang, People’s Republic of China; 2Department of Pain, The Affiliated Hospital of Jiujiang University, Jiujiang, People’s Republic of ...
Li X, Ding Z, Tong Y
doaj  

LncRCD: A Comprehensive Database for Pan-Cancer Characterization of lncRNAs Related to 12 Regulated Cell Death Types. [PDF]

Comput Struct Biotechnol J
Zhao H, Bai L, Li S, Sun Y, Liu W, Chen Z, Wang L, Hao C, Wang L.   +8 more
europepmc   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Influence of Long Non-Coding RNAs on Human Oocyte Development

Pharmacogenomics and Personalized Medicine
Leitong Wang, Baoshan Li, Dongkai Cheng Embryo Laboratory, Jinghua Hospital of Shenyang, Shenyang, Liaoning Province, 110000, People’s Republic of ChinaCorrespondence: Dongkai Cheng, Embryo Laboratory, Jinghua Hospital of Shenyang, No. 83, Zhongshan Road,
Wang L, Li B, Cheng D
doaj  

LncRNA TINCR rs2288947 Polymorphism as a Genetic Susceptibility Factor for Diabetic Retinopathy. [PDF]

J Ophthalmol
Liu J, Song J, Han S, Li Y, Chen P, Liu Q, Liu N, Wu M.   +7 more
europepmc   +1 more source

Elucidating the Role of SET as a Key Contributor to Neurodevelopmental Disability Within the 9q34.11 Deletion Syndrome Interval

Clinical Genetics, EarlyView.
This study reports a female proband with a de novo 9q34.11 deletion affecting SET, who underwent a 28‐year diagnostic odyssey after an atypical Rett syndrome clinical diagnosis. Genomic and proteomics analyses confirmed SET haploinsufficiency, refining the critical 9q34.11 region, and supporting speech therapy benefits in improving meaningful ...
Angelo Condell, Elaine Zhang, Tim Sikora, Sean Massey, Nicole J. Van Bergen, Min Wang, Cas Simons, Katrina M. Bell, Daniella H. Hock, David A. Stroud, David Francis, Wendy A. Gold, Martin B. Delatycki, John Christodoulou, Simranpreet Kaur   +14 more
wiley   +1 more source

The Janus face of host LncRNA in viral infections: Defender or collaborator? [PDF]

Commun Biol
Ding L, Pei G, Cheng Z.
europepmc   +1 more source