Results 191 to 200 of about 215,538 (386)

The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

International Journal of Cancer, EarlyView.
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley   +1 more source

LncRNAs in Inflammation

JACC: Basic to Translational Science, 2022
David A. Salisbury, Aneesh Kallapur, Giuliana G. Repetti, Josue Fraga, Jason Kim, Xiaohui Wu, Tamer Sallam   +6 more
openaire   +2 more sources

Deciphering the Role of LncRNAs in Osteoarthritis: Inflammatory Pathways Unveiled

Journal of Inflammation Research
Kangyi Hu, Haonan Wen, Ting Song, Zhixin Che, Yongjia Song, Min Song Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, People’s Republic of ChinaCorrespondence: Min Song; Yongjia Song, Clinical College of ...
Hu K, Wen H, Song T, Che Z, Song Y, Song M   +5 more
doaj  

TF2LncRNA: Identifying Common Transcription Factors for a List of lncRNA Genes from ChIP-Seq Data [PDF]

, 2014
Qinghua Jiang, Jixuan Wang, Yadong Wang, Rui Ma, Xiaoliang Wu, Yu Li   +5 more
openalex   +1 more source

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

International Journal of Cancer, EarlyView.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao, Junjie Cheng, Yiming Zheng, Jing Wu, Jia Fan, Haixiang Sun, Chao Gao   +6 more
wiley   +1 more source

LncRNAs in Immune and Stromal Cells Remodel Phenotype of Cancer Cell and Tumor Microenvironment

Journal of Inflammation Research
Wenbin Li,1,2,* Haohan Zhang,3,* Zuo You,4 Baozhu Guo5 1Department of Clinical Oncology, Qianjiang Hospital Affiliated to Renmin Hospital of Wuhan University, Qianjiang, Hubei, People’s Republic of China; 2Department of Clinical Oncology ...
Li W, Zhang H, You Z, Guo B
doaj  

Loss of METTL3 m6A methyltransferase results in short‐term progression and poor treatment outcome of bladder cancer patients

International Journal of Cancer, EarlyView.
What's New? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala, Stella Koroneou, Maria‐Alexandra Papadimitriou, Konstantina Panoutsopoulou, Konstantinos Soureas, Georgios‐Christos Giagkos, Panagiotis Levis, Dimitrios Linardoutsos, Konstantinos Stravodimos, Margaritis Avgeris, Andreas Scorilas   +10 more
wiley   +1 more source

Role of non-coding RNAs in skin photoaging

Pifu-xingbing zhenliaoxue zazhi
Skin photoaging, a phenomenon of premature skin aging due to prolonged exposure to ultraviolet (UV) radiation, manifests as wrinkles, loss of skin elasticity, pigmentation disorders, and age spots.
HE Zezhi, CHEN Jiazhen, WU Hui, SHEN Haojia, LI Runxiang, ZHU Huilan   +5 more
doaj   +1 more source

An Integrated Analysis of miRNA, lncRNA, and mRNA Expression Profiles [PDF]

, 2014
Li Guo, Yang Zhao, Sheng Yang, Hui Zhang, Feng Chen   +4 more
openalex   +1 more source

Mitochondrial fission protein 1 in the regulation of mitochondrial quality control: A cancer perspective

Interdisciplinary Medicine, EarlyView.
Background: Mitochondrial fission protein (FIS1), affecting energy metabolism and homeostasis, is crucial for mitochondrial quality control (MQC) and tumor progression. Key Points: It varies in expression across TME, influencing tumor progression.
Chao Wei, Xiaoling Yuan, Xiaoli Liu, Jia Feng, Miao Song, Xuexue Liu, Jiahong Zhou, Jinbo Liu   +7 more
wiley   +1 more source