Results 231 to 240 of about 215,538 (386)

Nanoscale Analysis beyond Imaging by Atomic Force Microscopy: Molecular Perspectives on Oncology and Neurodegeneration

open access: yesSmall Science, EarlyView.
Cancer and neurodegeneration share interconnected nanosized molecular pathways. Novel nanobiomedicine approaches promise targeted biomarkers and therapies. Atomic force microscopy (AFM) is invaluable to characterize nanosized biomolecular processes beyond imaging.
Carlos Marcuello   +5 more
wiley   +1 more source

“Lock and Key”: Binding Behavior of Malachite Green and Functional Nucleic Acids and Their Multidimensional Applications

open access: yesSmall Structures, EarlyView.
The review comprehensively summarizes the binding behaviors and multidimensional applications of malachite green with diverse functional nucleic acids. By integrating structural mechanisms, comparative analysis, and application strategies across eight domains, it provides theoretical guidance and future perspectives for developing intelligent nucleic ...
Keren Chen   +4 more
wiley   +1 more source

Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Recapitulating Its Importance and Defining Future Directions

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, mainly due to its aggressive nature, early metastasis, diagnosis at late stages, and limited response to systemic anticancer therapy. Perineural invasion (PNI), defined as the infiltration of neoplastic cells along nerve fibers and within nerve sheaths, is ...
Martin Lovecek   +10 more
wiley   +1 more source

Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models

open access: yesVIEW, EarlyView.
Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong   +7 more
wiley   +1 more source

The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMT-MET decision [PDF]

open access: gold, 2015
Imad Matouk   +5 more
openalex   +1 more source

Local regulation of gene expression by lncRNA promoters, transcription and splicing

open access: yesNature, 2016
J. Engreitz   +8 more
semanticscholar   +1 more source

Full‐length transcriptome profiling of true bug mitochondrial genomes reveals the unique transcriptional regulation during insect evolution

open access: yesInsect Science, EarlyView.
The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu   +6 more
wiley   +1 more source

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