Results 251 to 260 of about 215,538 (386)

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

BJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Narayan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan   +14 more
wiley   +1 more source

LncRNA-CTD suppresses metastasis and immune evasion by modulating snail1 and MHC-I expression in colorectal cancer. [PDF]

J Immunother Cancer
Xu N, Qiu H, Sun Y, Jin H, Yan S, Zhang F, Song Y, Zheng G, Liao D, Wei X, Luo L.   +10 more
europepmc   +1 more source

The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins [PDF]

, 2015
Hasan Imam, Aalia Shahr Bano, Paresh D. Patel, Prasida Holla, Shahid Jameel   +4 more
openalex   +1 more source

System level network data and models attack cancer drug resistance

British Journal of Pharmacology, EarlyView.
Drug resistance is responsible for >90% of cancer related deaths. Cancer drug resistance is a system level network phenomenon covering the entire cell. Small‐scale interactomes and signalling network models of drug resistance guide directed drug development.
Márk Kerestély, Dávid Keresztes, Levente Szarka, Borbála M. Kovács, Klára Schulc, Dániel V. Veres, Peter Csermely   +6 more
wiley   +1 more source

Transcriptome Sequencing Identifies Abnormal lncRNAs and mRNAs and Reveals Potentially Hub Immune-Related mRNA in Osteoporosis with Vertebral Fracture

Clinical Interventions in Aging
Rongxin Sun,1 Desheng Duan,2 Renzeng Li2 1Department of Orthopaedics, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, People’s Republic of China; 2Second Department of Orthopaedics, Third People’s Hospital of ...
Sun R, Duan D, Li R
doaj  

Integrative transcriptomics analysis reveals the metabolic regulatory functions of lncRNA in the livers of yak at different age stages. [PDF]

PLoS One
Fu H, Xia W, Fu F, Yi J, Wang W, Wei Y, Wang L.   +6 more
europepmc   +1 more source

Downregulation of lncRNA TUG1 Affects Apoptosis and Insulin Secretion in Mouse Pancreatic β Cells [PDF]

, 2015
Dandan Yin, Erbao Zhang, Lianghui You, Ning Wang, Lintao Wang, Xin Jin, Yanan Zhu, Lihua Cao, Qingxin Yuan, Wei De, Wei Tang   +10 more
openalex   +1 more source

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

Cancer Science, EarlyView.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao, Luyu Wang, Yi Ding, Lixian Yi, Mutian Han, Mengmeng Gu, Jian Wu   +6 more
wiley   +1 more source

Non-coding RNAs in gastric cancer: mechanisms and therapeutic prospects. [PDF]

Mol Cancer
Han Z, Liu W, Zhu Y, Sun Y, Sun D, Jia R, Yang Y, Qi H, Zhang L, Huo Y, Zhang N, Chai J, Yang M.   +12 more
europepmc   +1 more source

A Primary Role for the Tsix lncRNA in Maintaining Random X-Chromosome Inactivation [PDF]

, 2015
Srimonta Gayen, Emily Maclary, Emily Buttigieg, Michael Hinten, Sundeep Kalantry   +4 more
openalex   +1 more source