Results 51 to 60 of about 215,538 (386)

Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]

, 2019
Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico, Bertoli, Alessandro, Buson, Lisa, Cagnin, Stefano, Chemello, Francesco, Grespi, Francesca, Lanfranchi, Gerolamo, Martini, Paolo, Massimino, Maria L, Millino, Caterina, Pacchioni, Beniamina, Peggion, Caterina, Romualdi, Chiara, Scorrano, Luca   +13 more
core   +1 more source

The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma. [PDF]

, 2019
Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades.
Chang, Eric Y, Chu, Megan, High, Rachel A, Li, Wei Tse, Ongkeko, Weg M, Shen, Haotian, Wang-Rodriguez, Jessica, Wong, Lindsay M   +7 more
core   +1 more source

Role of noncoding RNA in vascular remodelling [PDF]

, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H., Bradshaw, Angela C., Deng, Lin   +2 more
core   +1 more source

Construction and analysis of lncRNA-lncRNA synergistic networks to reveal clinically relevant lncRNAs in cancer

Oncotarget, 2015
Long non-coding RNAs (lncRNAs) play key roles in diverse biological processes. Moreover, the development and progression of cancer often involves the combined actions of several lncRNAs. Here we propose a multi-step method for constructing lncRNA-lncRNA functional synergistic networks (LFSNs) through co-regulation of functional modules having three ...
Zishan Wang, Tingting Shao, Xia Li, Juan Chen, Jinwen Zhang, Chunjie Jiang, Juan Xu, Yongsheng Li   +7 more
openaire   +3 more sources

PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets [PDF]

, 2019
Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs.
Deshpande, Sumukh, England, Matthew, Shuttleworth, James, Taramonli, Sandy, Yang, Jianhua   +4 more
core   +4 more sources

Long non-coding RNA SOX2OT: Expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis [PDF]

, 2015
SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA which harbors one of the major regulators of pluripotency, SOX2 gene, in its intronic region.
Jazi, M.S., Mowla, S.J., Samaei, N.M., Shahryari, A.   +3 more
core   +1 more source

Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data

Nucleic Acids Res., 2020
An updated Lnc2Cancer 3.0 (http://www.bio-bigdata.net/lnc2cancer or http://bio-bigdata.hrbmu.edu.cn/lnc2cancer) database, which includes comprehensive data on experimentally supported long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) associated
Yue Gao, Shipeng Shang, Shuang Guo, Xin Li, Hanxiao Zhou, Hongjia Liu, Yue Sun, Junwei Wang, Peng Wang, Hui Zhi, Xia Li, Shangwei Ning, Yunpeng Zhang   +12 more
semanticscholar   +1 more source

Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model

Platelets, 2019
Platelet hyperaggregation and hypercoagulation are associated with increase of thrombogenic risk, especially in patients with type 2 diabetes (T2D).
Ming Zhou, Meng Gao, Yanwei Luo, Rong Gui, Hongwen Ji   +4 more
doaj   +1 more source

The lncRNA Neat1 promotes activation of inflammasomes in macrophages

Nature Communications, 2019
The inflammasome has an essential function in innate immune, responding to a wide variety of stimuli. Here we show that the lncRNA Neat1 promotes the activation of several inflammasomes.
Pengfei Zhang, Limian Cao, Rongbin Zhou, Xiaolu Yang, Mian Wu   +4 more
semanticscholar   +1 more source

Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma

Oncogene, 2020
RNA methylation is an important epigenetic modification. Recent studies on RNA methylation mainly focus on the m6A modification of mRNA, but very little is known about the m5C modification.
Zhen Sun, Songlei Xue, Meiying Zhang, Hui Xu, Xuming Hu, Shihao Chen, Yangyang Liu, M. Guo, H. Cui   +8 more
semanticscholar   +1 more source