Results 51 to 60 of about 167,789 (348)

Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders

Non-Coding RNA, 2021
Development is a complex process regulated both by genetic and epigenetic and environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression in several tissues including the brain.
V. Aliperti, J. Skonieczna, A. Cerase
semanticscholar   +1 more source

Shining a Spotlight on RNA m6A Modifications and Potential Targeted Immunotherapy in Ovarian Cancer

Clinical and Experimental Obstetrics & Gynecology
Objective: Ovarian cancer is one of the major gynecologic malignancies worldwide. Evidence indicates that N6-methyladenosine (m6A) modification is strongly related to cancer immunity.
Huaqin Pang, Weiping Zheng, Qiyun Lu, Huiya Zhang   +3 more
doaj   +1 more source

Regulation of lncRNA expression

Cellular and Molecular Biology Letters, 2014
AbstractLong non-coding RNAs (lncRNAs) are series of transcripts with important biological functions. Various diseases have been associated with aberrant expression of lncRNAs and the related dysregulation of mRNAs. In this review, we highlight the mechanisms of dynamic lncRNA expression.
Wu, Zhuomin, Liu, Xiaoxia, Liu, Li, Deng, Houliang, Zhang, Jingjing, Xu, Qian, Cen, Bohong, Ji, Aimin   +7 more
openaire   +2 more sources

The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis [PDF]

Non-Coding RNA, 2020
Long non-coding RNAs (lncRNAs) are a rapidly expanding field of research, with many new transcripts identified each year. However, only a small subset of lncRNAs has been characterized functionally thus far. To aid investigating the mechanisms of action by which new lncRNAs act, bioinformatic tools and databases are invaluable.
Holly R. Pinkney, Brandon M. Wright, Sarah D. Diermeier   +2 more
openaire   +3 more sources

Clinical significance of long non-coding RNA expression in esophageal cancer depending on the phenotype of the tumor stroma

Успехи молекулярной онкологии
Introduction. Esophageal squamous cell carcinoma is a dangerous oncological disease for which there are no relevant molecular-biological and biochemical markers for diagnosis, monitoring, and prognosis.
O. V. Kovaleva, P. A. Podlesnaya, E. S. Kudinova, M. A. Rashidova, V. V. Mochalnikova, A. N. Gratchev   +5 more
doaj   +1 more source

Association Between Single Nucleotide Polymorphisms Within lncRNA NONHSAT102891 and Depression Susceptibility in a Chinese Population

Neuropsychiatric Disease and Treatment, 2023
Peng Liang, Yingjie Sun, Yue Li, Yundan Liang Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, People’s Republic of ChinaCorrespondence: Yundan Liang, Department of Pathology and ...
Liang P, Sun Y, Li Y, Liang Y
doaj  

Two lncRNAs of Chinese cabbage confer Arabidopsis with heat and drought tolerance

Vegetable Research
Currently, frequent occurrences of abnormal weather events, including drought and extreme temperatures, are impacting plant growth and crop yields globally.
Yujie Wang, Shuqi Sun, Xuehuan Feng, Nan Li, Xiaoming Song   +4 more
doaj   +1 more source

Identification of lncRNAs-gene interactions in transcription regulation based on co-expression analysis of RNA-seq data

Mathematical Biosciences and Engineering, 2019
Long noncoding RNAs (lncRNA) play important roles in gene expression regulation in diverse biological contexts. Numerous studies have indicated that lncRNA-gene interactions are closely related to the occurrence and development of cancers.
Sijie Lu , Juan Xie, Yang Li, Bin Yu, Qin Ma, Bingqiang Liu   +5 more
doaj   +1 more source

Beyond the RNA-dependent function of LncRNA genes

eLife, 2020
While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last decade, the focus regarding their mechanisms of action has been primarily on the RNA product of these genes. Recent work on several lncRNAs genes demonstrates that not
Tamer Ali, Phillip Grote
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source