Results 31 to 40 of about 73,797 (157)
Cellular and molecular basis of thyroid autoimmunity
European Thyroid Journal, 2023 Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The two major clinical manifestations of AITD are Graves’ disease and Hashimoto’s thyroiditis (HT).
Joanna Bogusławska +3 more
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LncRNAs in ocular neovascularizations
International Journal of Ophthalmology, 2019 The prevalence of eye diseases worldwide is dramatically increasing and represents a major concern in underdeveloped and developed regions. Ocular diseases, previously associated with a higher depression risk, also impose a substantial economic burden on affected families, thus early detection and/or accurate treatment in order to avoid and prevent ...
Yacouba Cissé, Lang Bai, Min-Ting Chen
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The role of lncRNAs and exosomal lncRNAs in cancer metastasis
Biomedicine & Pharmacotherapy, 2023 Tumor metastasis is the main reason for cancer-related death, but there is still a lack of effective therapeutic to inhibit tumor metastasis. Therefore, the discovery and study of new tumor metastasis regulators is a prominent measure for cancer diagnosis and treatment. Long non-coding RNA (lncRNA) is a type of non-coding RNAs over 200 bp in length. It
Yutong, Zhang +10 more
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Journal of Inflammation Research, 2021 Rui Duan,1,* Si-Yu Wang,1,* Bin Wei,1 Yang Deng,2 Xin-Xin Fu,2 Peng-Yu Gong,1 Yan E,1 Xiao-Jin Sun,2 Hai-Ming Cao,1 Jian-Quan Shi,1 Teng Jiang,1 Ying-Dong Zhang1,2 1Department of Neurology, Nanjing First Hospital, Nanjing Medical University ...
Duan R +11 more
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Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms [PDF]
BioImpactsEpidermal growth factor receptor (EGFR) is a cell surface protein that plays a vital role in regulating cell growth and division. However, certain tumors, such as colorectal cancer (CRC), can exhibit an overexpression of EGFR, resulting in uncontrolled ...
Mostafa Akbarzadeh-Khiavi +2 more
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Regulation of lncRNA expression
Cellular and Molecular Biology Letters, 2014 AbstractLong non-coding RNAs (lncRNAs) are series of transcripts with important biological functions. Various diseases have been associated with aberrant expression of lncRNAs and the related dysregulation of mRNAs. In this review, we highlight the mechanisms of dynamic lncRNA expression.
Wu, Zhuomin +7 more
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The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis [PDF]
Non-Coding RNA, 2020 Long non-coding RNAs (lncRNAs) are a rapidly expanding field of research, with many new transcripts identified each year. However, only a small subset of lncRNAs has been characterized functionally thus far. To aid investigating the mechanisms of action by which new lncRNAs act, bioinformatic tools and databases are invaluable.
Holly R. Pinkney +2 more
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International Journal of General Medicine, 2021 Xiangpu Wang, Siyuan Guo, Xinli Zhou, Yupei Wang, Ting Zhang, Renji Chen Department of Oral and Maxillofacial Plastic and Trauma Surgery, Center of Cleft Lip and Palate Treatment, Beijing Stomatological Hospital, Capital Medical University, Beijing ...
Wang X +5 more
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New Insights into the Roles of Yes-Associated Protein (YAP1) in Colorectal Cancer Development and Progression [PDF]
Iranian Journal of Colorectal Research, 2019 Yes-associated protein (YAP1), the downstream effector of the Hippo pathway, plays important roles in the regulation of tissue reconstruction,stem cell proliferation, and development of different cancers.
Fariba Dehghanian +3 more
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Los ARNs no codificantes largos y su vinculación con las patologías testiculares
Anales de la Facultad de Medicina, 2019 Si bien la porción del genoma destinada a la síntesis de proteínas es muy pequeña, actualmente se sabe que casi todo el genoma se expresa bajo forma de ARNs no codificantes.
María F. Trovero, Adriana Geisinger
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