Results 101 to 110 of about 2,034,335 (282)

Numerical Determination of a Time-Dependent Source in a Modified Benjamin–Bona–Mahony Equation

Mathematics
In this paper, we consider a modified Benjamin–Bona–Mahony (BBM) equation, which, for example, arises in shallow-water models. We discuss the well-posedness of the Dirichlet initial-boundary-value problem for the BBM equation. Our focus is on identifying
Miglena N. Koleva, Lubin G. Vulkov
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

ON A PROBLEM FOR THE LOADED MIXED TYPE EQUATION WITH FRACTIONAL DERIVATIVE

, 2016
An existence and an uniqueness of solution of local boundary value problem with discontinuous matching condition for the loaded parabolic-hyperbolic equation involving the Caputo fractional derivative and Riemann-Liouville integrals have been ...
Abdullaev, O.K.
core   +1 more source

Non-local problems with integral gluing condition for loaded mixed type equations involving the Caputo fractional derivative

Electronic Journal of Differential Equations, 2016
In this work, we study the existence and uniqueness of solutions to non-local boundary value problems with integral gluing condition. Mixed type equations (parabolic-hyperbolic) involving the Caputo fractional derivative have loaded parts in Riemann ...
Obidjon Kh. Abdullaev, Kishin S. Sadarangani   +1 more
doaj  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

An analytic time jitter equation of NRZ signals in uniformly loaded PCB transmission lines

, 2018
An analytic equation was derived for the time jitter of digital NRZ signals due to inter-symbol interference in the PCB transmission lines loaded by DRAM chips which are located in uniform spacing.
Park, WK, Park, HJ, Park, JS, Cho, SI, Sohn, YS   +4 more
core  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

A non-local problem with discontinuous matching condition for loaded mixed type equation involving the Caputo fractional derivative

, 2016
This research work is devoted to investigations of the existence and uniqueness of the solution of a non-local boundary value problem with discontinuous matching condition for the loaded equation.
Sadarangani, Kishin, Abdullaev, O. K.
core   +1 more source