Results 71 to 80 of about 605,433 (293)

Source Identification for a Two-Dimensional Parabolic Equation with an Integral Constraint

Mathematics
We consider a two-dimensional parabolic problem subject to both Neumann and Dirichlet boundary conditions, along with an integral constraint. Based on the integral observation, we solve the inverse problem of a recovering time-dependent right-hand side ...
Miglena N. Koleva, Lubin G. Vulkov
doaj   +1 more source

Loading Bose condensed atoms into the ground state of an optical lattice

, 2004
We optimize the turning on of a one-dimensional optical potential, V_L(x,t) = S(t) V_0 cos^2(kx) to obtain the optimal turn-on function S(t) so as to load a Bose-Einstein condensate into the ground state of the optical lattice of depth V_0. Specifically,
Band, Y. B., Julienne, P. S., Trippenbach, M., Williams, C. J.   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Sub-Poissonian atom number fluctuations using light-assisted collisions

, 2012
We investigate experimentally the number statistics of a mesoscopic ensemble of cold atoms in a microscopic dipole trap loaded from a magneto-optical trap, and find that the atom number fluctuations are reduced with respect to a Poisson distribution due ...
A. Browaeys, A. Fuhrmanek, N. G. van Kampen, R. Bourgain, Y. R. P. Sortais   +4 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Boundary-value problems for a third-order loaded parabolic-hyperbolic equation with variable coefficients

Electronic Journal of Differential Equations, 2015
We prove the unique solvability of a boundary-value problems for a third-order loaded integro-differential equation with variable coefficients, by reducing the equation to a Volterra integral equation.
Bozor Islomov, Umida I. Baltaeva
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Finite-difference method for solving the first boundary value problem for a non-stationary loaded moisture transfer equation

Известия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. One of the important sections of the theory of differential equations is loaded equations. They allow us to model processes in which the influence of external factors significantly changes the behavior of the system.
M.Kh. Beshtokov
doaj   +1 more source

Integration of the Loaded Negative Order Nonlinear Schrodinger Equation in the Class of Periodic Functions

Известия Иркутского государственного университета: Серия "Математика"
In this paper, we consider the loaded negative order nonlinear Schrodinger equation (NSE) in the class of periodic functions. It is shown that the loaded negative order nonlinear Schrodinger equation can be integrated by the inverse spectral problem ...
M. M. Khasanov, I. D. Rakhimov, D. B. Azimov   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source