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Romanian Local Action Groups’ (LAGs) Economic Impact: A Solution to a Problem or a Perpetuating Status Quo of a Gimmick?

Transylvanian Review of Administrative Sciences
This article takes into consideration local action groups (LAGs) in the European Union and Romania in particular, in terms of resources needed, resources used, and measured impact on public services, infrastructures, and quality of life.
Daniel Buda, Antonia Pop
doaj +1 more source

In Vitro-In Vivo Correlations (IVIVC) for Predicting the Clinical Performance of Metronidazole Topical Creams Intended for Local Action. [PDF]

Pharmaceutics, 2023
Rath S, Kanfer I.
europepmc +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source

Hyperpolarization electrical signals induced by local action of moderate heating influence photosynthetic light reactions in wheat plants. [PDF]

Front Plant Sci, 2023
Yudina L +6 more
europepmc +1 more source

‘Local Food’ Systems in County Durham: The capacities of community initiatives and local food businesses to build a more resilient local food system [PDF]

, 2011
This thesis provides a critical assessment of the capacities of ‘local food’ businesses and community-led local food initiatives - in County Durham, North East England - to build resilience into our food systems.
MYCOCK, AMY,ELIZABETH
core

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source

Need to Know Review Number two: What Local Government Needs to Know about Public Health

, 2014
This review of existing research on local government and public health focuses on the leadership role of local government in developing local public health systems that are capable of addressing the wider determinants of ...
South, J, Hunter, DJ, Gamsu, M
core

ACTIONS OF LOCAL ANÆSTHETICS

Journal of Pharmacy and Pharmacology, 1951
O, PECZENIK, G B, WEST
openaire +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source

Public priorities for local action to reduce the health impacts of climate change: Evidence from a UK survey. [PDF]

Public Health Pract (Oxf), 2022
Harrison A, Graham H.
europepmc +1 more source

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