Results 101 to 110 of about 1,104,255 (313)

The limits of partnership : an exit-action strategy for local democratic inclusion [PDF]

open access: yes, 2007
The challenge of enhancing the `democratic anchorage' of partnerships has become a central concern in policy studies. Radical reform proposals designed to level the deliberative playing field include community veto powers and the appointment of neutral ...
Davies, Jonathan S., Jonathan S. Davies
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

BUDGET ANALYSIS IN THE LOCAL ACTION GROUPS [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
The objective of this article is to highlight the importance of budgets for any organization, there is an interdependence relationship between the degree of the objectives achievement and transfer them into the budget.
BUMBESCU SORINA SIMONA
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The role of farmers in Local Action Groups: The case of the national network of the Local Action Groups in the Czech Republic

open access: yesAgricultural Economics (AGRICECON), 2012
The social inclusion of different rural population groups is one of the objectives of the Rural Development Programme of the Czech Republic for the period of 2007-2013.
Miloslav DELIN
doaj   +1 more source

Has UK local government action improved local air quality? A Bristol case study [PDF]

open access: yes, 2015
© 2015 WIT Press. In 2013, the UK exceeded the EU limit value for nitrogen dioxide (NO2) annual mean at 31 of its 43 zones and agglomerations. Current government predictions are that full compliance will not be achieved until after 2030, with 65% zones ...
Hayes, E. T.   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Local Art, Local Action: A Proposal for Deliberating on and about Main Street

open access: yesJournal of Deliberative Democracy, 2013
In every campaign, politicians make promises. They spell out their hopes and dreams for their constituents and describe the dystopia that would exist should their opponent be elected instead.
Anna Wolfe
doaj   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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