From Local Action to Global Policy: A Comparative Policy Content Analysis of National Policies to Address Musculoskeletal Health to Inform Global Policy Development. [PDF]
Schneider CH +8 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Local action to protect communities in Nigeria
Collaborative, creative initiatives in Nigeria helped protect local communities from much of the impact of Boko Haram violence. When international agencies arrived, however, they ignored these efforts.
Margee Ensign
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
ALARA-BALT Australasian Action Learning, Action Research Conference 2020
Announcement of ALARA-BALT Australasian Action Learning, Action Research Conference 2020 in Launceston, Tasmania on 8-10 November ...
Bradley, Colin
core
Involving young people in action research
An opportunity for a range of practitioners to explore issues such as how young people can be supported as volunteers within local areas, particularly as local advocates, in gathering information and data on issues affecting young ...
Youth Action Northern Ireland (YANI), None +2 more
core +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Overcoming structural barriers to sharing power with communities in global health research priority-setting: Lessons from the Participation for Local Action project in Karnataka, India. [PDF]
Pratt B, Seshadri T, Srinivas PN.
europepmc +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Global emergency, local action: safeguarding Pakistan from Mpox
Madam, Monkeypox (Mpox) is a zoonotic viral disease that the World Health Organization declared a public health emergency of international concern he following a surge in Africa and spread to neighbouring countries.
Uswa Hasana, Wahhaj Munir, Adil Khan
doaj +1 more source

