Results 101 to 110 of about 9,959,275 (238)

From Local Action to Global Policy: A Comparative Policy Content Analysis of National Policies to Address Musculoskeletal Health to Inform Global Policy Development. [PDF]

open access: yesInt J Health Policy Manag, 2023
Schneider CH   +8 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Local action to protect communities in Nigeria

open access: yesForced Migration Review, 2016
Collaborative, creative initiatives in Nigeria helped protect local communities from much of the impact of Boko Haram violence. When international agencies arrived, however, they ignored these efforts.
Margee Ensign
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

ALARA-BALT Australasian Action Learning, Action Research Conference 2020

open access: yes, 2019
Announcement of ALARA-BALT Australasian Action Learning, Action Research Conference 2020 in Launceston, Tasmania on 8-10 November ...
Bradley, Colin
core  

Involving young people in action research

open access: yes, 2006
An opportunity for a range of practitioners to explore issues such as how young people can be supported as volunteers within local areas, particularly as local advocates, in gathering information and data on issues affecting young ...
Youth Action Northern Ireland (YANI), None   +2 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Global emergency, local action: safeguarding Pakistan from Mpox

open access: yesJournal of the Pakistan Medical Association
Madam, Monkeypox (Mpox) is a zoonotic viral disease that the World Health Organization declared a public health emergency of international concern he following a surge in Africa and spread to neighbouring countries.
Uswa Hasana, Wahhaj Munir, Adil Khan
doaj   +1 more source

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