Results 81 to 90 of about 1,104,255 (313)

Beyond PRA: experiments in facilitating local action in water management

open access: yes, 2005
As a tool both for research and for structuring community-level interaction, Participatory Rural Appraisal (PRA) is now well embedded in development practice.
Sekhar Nandi, Snehangshu, Schaap, Wouter
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The role of digital participation platforms in risk-informed development: A case study of Surabaya, Indonesia

open access: yesProgress in Disaster Science
There is growing policy consensus around the need for development to be risk-informed. In parallel, digital technologies are increasingly deployed to enhance participation within a wide range of policy domains, particularly in urban settings.
Ronan McDermott   +6 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Action learning/action research knowledge development and translation: a 'learning conference' experience

open access: yes, 2013
This article tells a 'learning conference' story about the establishment of a local action learning and action research (ALAR) Conversation Group in a regional city in Australia, which occurred between the Action Learning and Action Research Association (
Lynn, Robyn, Redman-MacLaren, Michelle
core  

Local Government Excellence Programme prospectus – overview [PDF]

open access: yes, 2016
The 2015 New Zealand Local Government Survey found residents and businesses had a low awareness of the full services councils provide and the value they bring.
Local Government New Zealand
core  

Local level action on FCTC Article 5.3 in Bangladesh

open access: yes, 2018
Background and challenges to implementation Throughout Bangladesh, the tobacco industry regularly organizes events and parties to which it invites government officials and sponsors local events.
Gaous Pearee   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Involving young people in action research

open access: yes, 2006
An opportunity for a range of practitioners to explore issues such as how young people can be supported as volunteers within local areas, particularly as local advocates, in gathering information and data on issues affecting young ...
Youth Action Northern Ireland (YANI), None   +2 more
core  

Spatial determinants of local government action on climate change: an analysis of local authorities in England

open access: yes, 2014
The engagement of UK local authorities is vital if national government is to meet its climate change commitments. However, with no mandatory targets at local government level, other drivers must explain engagement. Using a Geographic Information System,
Mann, Sarah   +2 more
core   +1 more source

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