Results 91 to 100 of about 1,104,255 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Local geodiversity action plans - setting to context for geological conservation

, 2006
The book is available at http://naturalengland.etraderstores.com/NaturalEnglandShop/Product.aspx?ProductID=6d726d7a-c9d5-4ff5-b0f2-325653eaef15. This book is not available through ChesterRep.This booklet discusses local geodiversity action plans (LGAPs ...
Burek, Cynthia V., Potter, Jacqueline
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Why are toilets not used? Using system effects modelling to understand stakeholder perceptions on the impacts and barriers to Taenia solium control in Eastern and Western Uganda

BMC Veterinary Research
Taenia solium taeniasis/cysticercosis in humans and pigs remains endemic to Uganda. Although, looking at the lifecycle of the parasite, the risk factors are well known, and many biomedical control options exist – no substantial progress has been made in ...
Nicholas Ngwili, Salaviriuse Ahimbisibwe, Derrick N. Sentamu, Luke Craven, Lian F. Thomas, Kristina Roesel   +5 more
doaj   +1 more source

Mechanisms of benzydamine action against local inflammatory process

Медицинский совет, 2019
Local inflammatory diseases caused by various infections are one of the most common pathologies in medical practice. For example, tonsillopharyngitis. This disease is extremely frequent for a physician’s practice.
G. V. Poryadin, J. M. Salmasi, A. N. Kazimirsky   +2 more
doaj   +1 more source

Enhancing learning with authoritative actions: Reflective practice of positive power

, 2012
Drawing from classic power perspective, my reflective practice illuminates how power action, traditionally recognized as negative and detrimental to teaching process and learning outcomes, could be shaped in a positive way to enhance learning. Insights
Chen, Wenshin
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Action Research and Development for Intrinsic Innovation in Social Service Administration: Prototyping and Proof of Concept in Small Scale Start-Ups

, 2013
In considering the significance of the small-scale start-up in social service agencies and community development, the authors address how community-based participatory action research can serve as an innovation strategy in social service administration ...
Moxley, David P., Thompson, Valerie R., Deacon, Zermarie   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Practitioner reflection Growing our knowledge, improving our practice - reflecting on how doing participatory action research over a period of time shifts the way you understand and do the work

, 2013
This article describes and reflects on the experience of the Reconnect East Arnhem early intervention service in using participatory action research (PAR).
Parker, Michelle
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