Results 71 to 80 of about 220,118 (258)

Using regression to improve local convergence

open access: yes2007 IEEE Congress on Evolutionary Computation, 2007
Traditionally Evolutionary Algorithms (EAs) choose candidate solutions based on their individual fitnesses, usually without directly looking for patterns in the fitness landscape discovered. These patterns often contain useful information that could be used to guide the EA to the optimum. While an EA is able to quickly locate the general area of a peak,
Stefan Bird, Xiaodong Li 0001
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Local Convergence of an Optimal Eighth Order Method under Weak Conditions

open access: yesAlgorithms, 2015
We study the local convergence of an eighth order Newton-like method to approximate a locally-unique solution of a nonlinear equation. Earlier studies, such as Chen et al. (2015) show convergence under hypotheses on the seventh derivative or even higher,
Ioannis K. Argyros   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Convergence and Dynamics of Schröder’s Method for Zeros of Analytic Functions with Unknown Multiplicity

open access: yesMathematics
In this paper, we investigate the local convergence of Schröder’s method for finding zeros of analytic functions with unknown multiplicity. Thus, we obtain a convergence theorem that provides exact domains of initial points together with error estimates ...
Plamena I. Marcheva, Stoil I. Ivanov
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Local Convergence of Jarratt-Type Methods with Less Computation of Inversion Under Weak Conditions

open access: yesMathematical Modelling and Analysis, 2017
We present a local convergence analysis for Jarratt-type methods in order to approximate a solution of a nonlinear equation in a Banach space setting. Earlier studies cannot be used to solve equations using such methods.
Ioannis K. Argyros, Santhosh George
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

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