Results 51 to 60 of about 220,118 (258)

Local convergence of the Gauss-Newton-Kurchatov method under generalized Lipschitz conditions

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2021
We investigate the local convergence of the Gauss-Newton-Kurchatov method for solving nonlinear least squares problems. This method is a combination of Gauss-Newton and Kurchatov methods and it is used for problems with the decomposition of the operator.
S.M. Shakhno, H.P. Yarmola
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

On C-To-R-Based Iteration Methods for a Class of Complex Symmetric Weakly Nonlinear Equations

open access: yesMathematics, 2020
To avoid solving the complex systems, we first rewrite the complex-valued nonlinear system to real-valued form (C-to-R) equivalently. Then, based on separable property of the linear and the nonlinear terms, we present a C-to-R-based Picard iteration ...
Min-Li Zeng, Guo-Feng Zhang
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Convergence Analysis and Complex Geometry of an Efficient Derivative-Free Iterative Method

open access: yesMathematics, 2019
To locate a locally-unique solution of a nonlinear equation, the local convergence analysis of a derivative-free fifth order method is studied in Banach space.
Deepak Kumar   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Local convergence of some high order iterative methods based on the decomposition technique using only the first derivative [PDF]

open access: yesSurveys in Mathematics and its Applications, 2017
We present a local convergence analysis of some high order iterative methods based on the decomposition technique using only the first derivative for solving equations in order to approximate a solution of a nonlinear equation.
Ioannis K. Argyros, Santhosh George
doaj  

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