Results 101 to 110 of about 302,578 (216)

High-Precision 3D Printing of Microporous Cochlear Implants for Personalized Local Drug Delivery. [PDF]

J Funct Biomater, 2023
Isaakidou A, Apachitei I, Fratila-Apachitei LE, Zadpoor AA.   +3 more
europepmc   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source

Peripheral artery disease and local drug delivery: a review of disease pathology and drug delivery systems for therapy below the knee. [PDF]

Exp Biol Med (Maywood)
Akers NM, Dugas TR.
europepmc   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies. [PDF]

Pharmaceutics
Rakoczy R, Machoy-Rakoczy M, Gutowska I.
europepmc   +1 more source

Local Drug Delivery Strategies towards Wound Healing. [PDF]

Pharmaceutics, 2023
Tiwari R, Pathak K.
europepmc   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Advances in Local Drug Delivery for Periodontal Treatment: Present Strategies and Future Directions. [PDF]

Biomolecules
Nakajima M, Yanagawa M, Takikawa H, Thien TT, Zegarra-Caceres L, Yan C, Tabeta K.   +6 more
europepmc   +1 more source

Multi-scale in silico and ex silico mechanics of 3D printed cochlear implants for local drug delivery. [PDF]

Front Bioeng Biotechnol, 2023
Isaakidou A, Ganjian M, van Hoften R, Saldivar MC, Leeflang MA, Groetsch A, Wątroba M, Schwiedrzik J, Mirzaali MJ, Apachitei I, Fratila-Apachitei LE, Zadpoor AA.   +11 more
europepmc   +1 more source

Microspheres for Local Drug Delivery

, 2016
About 40.000 people in The Netherlands suffer from kidney disease. When kidney function stops completely, dialysis and a kidney transplant are the only available treatment options. Because of a shortage in donor organs many patients have to depend on dialysis. However, dialysis has severe complications and remains a health threat.Within this project we
openaire   +1 more source