Results 81 to 90 of about 885,184 (197)

Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance

open access: yesNature Communications
The resistance of pests to common insecticides is a global issue that threatens food production worldwide. Diamide insecticides target insect ryanodine receptors (RyRs), causing uncontrolled calcium release from the sarcoplasmic and endoplasmic reticulum.
Lianyun Lin   +15 more
doaj   +1 more source

Evaluation and design of a novel drug delivery device for treating tumor-related cerebral edema [PDF]

open access: yes, 2010
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p. 47-53).Tumor-related cerebral edema is a debilitating medical condition
Shair, Kamal A. (Kamal Abdo)
core  

Local Application of Antibiotics in Periodontal Pockets

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011
Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such
B Amoian   +3 more
doaj  

Intraperiodontal pocket: An ideal route for local antimicrobial drug delivery

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2012
Periodontal pockets act as a natural reservoir filled with gingival crevicular fluid for the controlled release delivery of antimicrobials directly.
Sreeja C Nair, K R Anoop
doaj   +1 more source

Peptide hydrogels as mucoadhesives for local drug delivery

open access: yesInternational Journal of Pharmaceutics, 2014
We have investigated the possibility of using self-assembling peptide-based viscous solutions and hydrogels as mucoadhesives for the improved delivery of drugs to local mucosal surfaces. The stability of the samples under flow after deposition on a mucosal surface mimic was studied using a simplified in vitro model.
Tang, Claire   +2 more
openaire   +2 more sources

Endovascular Drug Delivery

open access: yesLife
Drug-eluting stents (DES) and balloons revolutionize atherosclerosis treatment by targeting hyperplastic tissue responses through effective local drug delivery strategies.
Claudiu N. Lungu   +2 more
doaj   +1 more source

Packaging for a drug delivery microelectromechanical system [PDF]

open access: yes, 2005
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.Includes bibliographical references (p. 52-55).Local drug delivery is a fast expanding field, and has been a center of attention for researchers in ...
Ho Duc, Hong Linh, 1978-
core  

Chitosan in Mucoadhesive Drug Delivery: Focus on Local Vaginal Therapy

open access: yesMarine Drugs, 2015
Mucoadhesive drug therapy destined for localized drug treatment is gaining increasing importance in today’s drug development. Chitosan, due to its known biodegradability, bioadhesiveness and excellent safety profile offers means to improve mucosal drug ...
Toril Andersen   +5 more
doaj   +1 more source

Expanding Use of Magnesium Sulfate for Treatment of Pre-eclampsia and Eclampsia [PDF]

open access: yes, 2014
Pre-eclampsia/eclampsia is a serious condition that can develop during pregnancy, even in women with no risk factors. Although there is little understanding of what causes pre-eclampsia/eclampsia, there is an effective treatment for this condition which,
Elisa Wells   +3 more
core  

Biocompatability of Hydroxyapatite Composite as a Local Drug Delivery System

open access: yesJournal of Orthopaedic Surgery, 2006
Purpose. To investigate the biocompatibility of hydroxyapatite composite (hydroxyapatite, plaster of Paris, and chitosan) impregnated with gentamicin, fosfomycin, imipenem, or amphotericin B. Methods.
A Krisanapiboon   +2 more
doaj   +1 more source

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