Results 61 to 70 of about 885,184 (197)

Chewing Gums as a Drug Delivery Approach for Oral Health

International Journal of Dentistry, 2022
Background. Drug delivery approaches with the shortest therapeutic period and the lowest side effects have always been considered a sublime target in the medical sciences.
Morteza Banakar, Sedigheh Moayedi, Erfan Shamsoddin, Zahra Vahedi, Mohammad Hasan Banakar, Seyyed Mojtaba Mousavi, Dinesh Rokaya, Kamran Bagheri Lankarani   +7 more
doaj   +1 more source

Colon-Targeted Oral Drug Delivery Systems: Design Trends and Approaches [PDF]

, 2015
Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome, chronic pancreatitis, and colonic cancer.
Amidon, Seth, Brown, Jack, Dave, Vivek S
core   +1 more source

Overcoming therapeutic challenges in acute myeloid leukemia: active targeting strategies by nano-drug delivery systems

Journal of Translational Medicine
Background Acute myeloid leukemia (AML) is a highly aggressive hematological malignancy characterized by poor overall survival and high relapse rates.
Yuqian Tang, Jiaxin Li, Wu Ye, Yiwen Du, Ying Zhang, Yunxia Ye, Yuping Gong   +6 more
doaj   +1 more source

Preparation and Characterization of Simvastatin Loaded PLGA Microparticles forTissue Engineering Applications [PDF]

, 2012
Simvastatin has been reported to promote osteoblastic activity and inhibit osteoclastic activity. The successful use of simvastatin to promote in vivo bone formation depends on the local concentration, and there have been continuous efforts to find an ...
Ciardelli, Gianluca, Daly, Jacqueline, Montevecchi, Franco M, Muttu, Clara, Nandagiri, Vijay K, Ramtoola, Ziebun   +5 more
core   +1 more source

Tissue compatibility of poly(hydroxypropylglutamate)-prazosin conjugates [PDF]

, 1992
Biocompatibility of an injectable biodegradable drug delivery system for prazosin was investigated in Sprague-Dawley rats by histological studies after subcutaneous injection ofpoly(hydroxypropyl glutamate)-prazosin (PHPG-prazosin) conjugate particles ...
Anderson, James M., Feijen, Jan, Kim, Sung Wan, Li, Xiaoling, Yamaguchi, Kazuhiro   +4 more
core   +2 more sources

Calcium Phosphate/Hyaluronic Acid Composite Hydrogels for Local Antiosteoporotic Drug Delivery

Frontiers in Bioengineering and Biotechnology, 2022
Despite the bone ability of self-regeneration, large bone defects require surgical intervention. Likewise, when it comes to osteoporotic bone fractures, new approaches should be considered a supportive mechanism for the surgery. In recent years, more and
Alise Svarca, Alise Svarca, Andra Grava, Andra Grava, Arita Dubnika, Arita Dubnika, Anna Ramata-Stunda, Raimonds Narnickis, Kristine Aunina, Kristine Aunina, Eleonora Rieksta, Eleonora Rieksta, Martins Boroduskis, Inga Jurgelane, Inga Jurgelane, Janis Locs, Janis Locs, Dagnija Loca, Dagnija Loca   +18 more
doaj   +1 more source

A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis. [PDF]

, 2013
BACKGROUND: The success of programs to eliminate lymphatic filariasis (LF) depends in large part on their ability to achieve and sustain high levels of compliance with mass drug administration (MDA). This paper reports results from a comprehensive review
Fischer, Peter U, Krentel, Alison, Weil, Gary J   +2 more
core   +4 more sources

Recent advances in musculoskeletal local drug delivery [PDF]

Acta Biomaterialia, 2019
Musculoskeletal disorders are a significant burden on the global economy and public health. Advanced drug delivery plays a key role in the musculoskeletal field and holds the promise of enhancing the repair of degenerated and injured musculoskeletal tissues.
Shichao Zhang, Malcolm Xing, Bingyun Li
openaire   +2 more sources

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura, Chicca, Milvia, DANTI, SERENA, Franceschini, Valeria, Martini, Alessandro, Simoni, Edi, Valente, Filippo   +6 more
core   +2 more sources

Principles of Local Drug Delivery to the Inner Ear [PDF]

Audiology and Neurotology, 2009
As more and more substances have been shown in preclinical studies to be capable of preventing damage to the inner ear from exposure to noise, ototoxic drugs, ischemia, infection, inflammation, mechanical trauma and other insults, it is becoming very important to develop feasible and safe methods for the targeted delivery of drugs to specific regions ...
Alec N, Salt, Stefan K, Plontke
openaire   +2 more sources