Results 51 to 60 of about 885,184 (197)
Polysaccharide based formulations for mucosal drug delivery: A review [PDF]
, 2015 There has been increased interest in novel drug delivery systems to be administered via mucosal routes as an alternative to the currently used traditional routes such as parenteral (injections) and oral routes of administration.
Boateng, Joshua +2 more
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Polymeric gels for intravaginal drug delivery [PDF]
, 2017 This document is the Accepted Manuscript version of the following article: Michael T. Cook, and Marc b. Brown, ‘Polymeric gels for intravaginal drug delivery’, Journal of Controlled Release, Vol. 270: 145-157, January 2018. Under embargo until 6 December
Brown, Marc, Cook, Michael
core +2 more sources
Herbal Local Drug Delivery: A Narrative Review
Indian Journal of Dental SciencesPeriodontitis is a complex and chronic inflammation of the periodontium and can be diagnosed clinically by gingival inflammation, attachment loss, and loosening of teeth.
Akanksha Mohan Karale +3 more
doaj +1 more source
Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions [PDF]
, 2017 The vascular endothelium presents a major transport barrier to drug delivery by only allowing selective extravasation of solutes and small molecules. Therefore, enhancing drug transport across the endothelial barrier has to rely on leaky vessels arising ...
Bao, Gang +7 more
core +1 more source
Nucleoside‐Based Self‐Assembling Drugs for Localized Drug Delivery [PDF]
ChemMedChem, 2018 AbstractWe have synthesized a range of gelators based on the nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and transmission electron microscopy. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicating the ...
Kathryn J. Skilling +6 more
openaire +2 more sources
Advances in orally targeted drug delivery to colon
Journal of Advanced Pharmaceutical Technology & Research, 2019 Colon-specific drug delivery is critical for treating diseases of colon, such as colon cancer, amoebiasis, irritable bowel syndrome, and inflammatory bowel disease. This study reviews the effects of targeted oral drug delivery on patient by measuring the
Nagina Belali +2 more
doaj +1 more source
pH-Sensitive Chitosan–Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells [PDF]
, 2019 Chitosan has been extensively studied as a genetic drug delivery platform. However, its efficiency is limited by the strength of DNA and RNA binding.
Korzhikov-Vlakh, Viktor +7 more
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Local inner-ear drug delivery and pharmacokinetics [PDF]
Drug Discovery Today, 2005 Several drugs that are applied directly to the inner ear are in widespread clinical use for the treatment of inner-ear disorders. Many new substances and drug delivery systems specific to the inner ear are under development and in some cases are being evaluated in animal experiments and in clinical studies. However, the pharmacokinetics of drugs in the
Alec N, Salt, Stefan K R, Plontke
openaire +2 more sources
Plant Exosome-like Nanoparticles as Biological Shuttles for Transdermal Drug Delivery
Bioengineering, 2023 Exosomes act as emerging transdermal drug delivery vehicles with high deformability and excellent permeability, which can be used to deliver various small-molecule drugs and macromolecular drugs and increase the transdermal and dermal retention of drugs,
Ye Wang +6 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Drug eluting ureteral stent is an effective means for local drug delivery to the urinary tract. It can potentially solve a variety of upper urinary tract problems, such as stent-related urinary tract infections and discomfort, ureteral stricture, and ...
Hongli Shan +6 more
doaj +1 more source