Results 51 to 60 of about 10,043,064 (337)
Evaluation of Different Local Drug Delivery Systems in Treatment of Periodontitis: An Institutional Study [PDF]
, 2023 Periodontal disease can be treated in both non-surgical and surgical therapy. There could be a possible reason why non-surgical therapy causes failure due to bacteria virulent factors and also the depth of periodontal pocket is greater than the ...
Kharidhi Laxman Vandana, Vangara Aditya
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Local drug delivery to prevent restenosis [PDF]
Journal of Vascular Surgery, 2013 Despite significant advances in vascular biology, bioengineering, and pharmacology, restenosis remains a limitation to the overall efficacy of vascular reconstructions, both percutaneous and open. Although the pathophysiology of intimal hyperplasia is complex, a number of drugs and molecular tools have been identified that can prevent restenosis ...
Seedial, Stephen M. +6 more
openaire +2 more sources
Targeted Microbubbles for Drug, Gene, and Cell Delivery in Therapy and Immunotherapy [PDF]
, 2023 Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through bioconjugation of a ligand, drug and/or cell.
Mark A. Borden +3 more
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Avoiding a sticky situation: bypassing the mucus barrier for improved local drug delivery
Trends in Molecular Medicine, 2021 The efficacy of drugs administered by traditional routes is limited by numerous biological barriers that preclude reaching the intended site of action. Further, full body systemic exposure leads to dose-limiting, off-target side effects.
Hannah C. Zierden +5 more
semanticscholar +1 more source
Stent development and local drug delivery [PDF]
British Medical Bulletin, 2001 Stent implantation has become the new standard angioplasty procedure. In-stent re-stenosis remains the major limitation of coronary stenting. Re-stenosis is related to patient-, lesion- and procedure-specific factors. Patient-specific factors can not be influenced to any extent.
Regar, Evelyn +2 more
openaire +2 more sources
Microspheres for local drug delivery in bone joints [PDF]
, 2019 Bone joints are the junctions between bones in the body which link the skeletal system into a functional whole. A joint may be the connecting point between two or more bones.
Soundrapandian, Chidambaram +1 more
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Floating type drug delivery system: a review [PDF]
, 2019 Floating Type drug delivery system retains the dosage form for a long span. They provide local delivery to specific region like stomach and proximal small intestine and shows better bioavailability and improve therapeutic activity and substantial benefit
Datir, S K, Patil, P.B., Saudagar, R.B.
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Selective drug delivery to the retinal cells: Biological barriers and avenues
, 2023 Retinal drug delivery is a challenging, but important task, because most retinal diseases are still without any proper therapy. Drug delivery to the retina is hampered by the anatomical and physiological barriers resulting in minimal bioavailability ...
Arto Urtti +15 more
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Silica nanoparticles in transmucosal drug delivery [PDF]
, 2020 Transmucosal drug delivery includes the administration of drugs via various mucous membranes, such as gastrointestinal, nasal, ocular, and vaginal mucosa.
Ng, Keng Wooi +7 more
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Prevention of Restenosis by Local Drug Delivery
Journal of Cardiovascular Pharmacology and Therapeutics, 1996 Local drug therapy for preventing restenosis after angioplasty has been investigated for over a decade. Biologically active agents ranging from drugs to genes can be delivered locally using a wide variety of catheters. Microspheres, liposomes, and polymers have been used to enhance drug retention at the delivery site.
, Makkar +3 more
openaire +2 more sources