Results 31 to 40 of about 20,684,051 (242)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dissonant Representations of Visual Space in Prefrontal Cortex during Eye Movements
Summary: We used local field potentials (LFPs) and spikes to investigate representations of visual space in prefrontal cortex and the dynamics of those representations during eye movements.
Xiaomo Chen, Marc Zirnsak, Tirin Moore
doaj +1 more source
Brain control by locus coeruleus (LC) neurons involves afferent glutamate (Glu) inputs. In newborns, LC Glu receptors and responses may be sparse due to immaturity of the brain circuits providing such input.
Bijal Rawal, Klaus Ballanyi
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
TinyLFP: A Tiny Local-Field-Potential Sensor
TinyLFP: A Tiny Local-Field-Potential ...
Abbas Kouzani (13079637) +1 more
core
Guidelines on sustainable mobility : shared transport [PDF]
This is the fourth published guideline document, in a series of documents which are being published under the Resident First project headed by the Local Councils’ Association (LCA) and endorsed by all Local Councils in Malta and Gozo.
Zammit, Antoine +1 more
core
A Low-Cost Modular Multi-Region Electrode for Distributed Network Recording and Brain State Decoding
Background: Precise decoding of brain states is essential for closed-loop neuromodulation, but current electrodes and recording strategies are inadequate.
Bo-Yu Wang +6 more
doaj +1 more source
Computing the Local Field Potential (LFP) from Integrate-and-Fire Network Models.
Leaky integrate-and-fire (LIF) network models are commonly used to study how the spiking dynamics of neural networks changes with stimuli, tasks or dynamic network states. However, neurophysiological studies in vivo often rather measure the mass activity
Alberto Mazzoni +5 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

