Results 41 to 50 of about 909,585 (312)

The relationship between dendritic branch dynamics and CPEB-labeled RNP granules captured in vivo

Frontiers in Neural Circuits, 2009
Cytoplasmic Polyadenylation Element Binding protein (CPEB) is an RNA binding protein involved in dendritic delivery of mRNA and activity-dependent, polyadenylation-induced translation of mRNAs in the dendritic arbor.
Jennifer E Bestman, Hollis Cline
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Cystatin B Involvement in Synapse Physiology of Rodent Brains and Human Cerebral Organoids

Frontiers in Molecular Neuroscience, 2019
Cystatin B (CSTB) is a ubiquitous protein belonging to a superfamily of protease inhibitors. CSTB may play a critical role in brain physiology because its mutations cause progressive myoclonic epilepsy-1A (EPM1A), the most common form of progressive ...
Eduardo Penna, Angela Cerciello, Angela Chambery, Rosita Russo, Filippo M. Cernilogar, Emilia Maria Pedone, Carla Perrone-Capano, Carla Perrone-Capano, Silvia Cappello, Rossella Di Giaimo, Rossella Di Giaimo, Marianna Crispino   +11 more
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Local sharing as a predominant determinant of synaptic matrix molecular dynamics. [PDF]

PLoS Biology, 2006
Recent studies suggest that central nervous system synapses can persist for weeks, months, perhaps lifetimes, yet little is known as to how synapses maintain their structural and functional characteristics for so long.
Shlomo Tsuriel, Ran Geva, Pedro Zamorano, Thomas Dresbach, Tobias Boeckers, Eckart D Gundelfinger, Craig C Garner, Noam E Ziv   +7 more
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Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance. [PDF]

, 2012
Background and aimsThe root apical meristem (RAM) is the plant stem cell niche which provides for the formation and continuous development of the root.
Doroshkov, AV, Kazantsev, FV, Kochetov, AV, Kolchanov, NA, Likhoshvai, VA, Mironova, VV, Mjolsness, E, Novoselova, ES, Omelyanchuk, NA   +8 more
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Intra-axonal Synthesis of SNAP25 Is Required for the Formation of Presynaptic Terminals

Cell Reports, 2017
Localized protein synthesis is a mechanism for developing axons to react acutely and in a spatially restricted manner to extracellular signals. As such, it is important for many aspects of axonal development, but its role in the formation of presynapses ...
Andreia F.R. Batista, José C. Martínez, Ulrich Hengst   +2 more
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The malleable brain: plasticity of neural circuits and behavior: A review from students to students [PDF]

, 2017
One of the most intriguing features of the brain is its ability to be malleable, allowing it to adapt continually to changes in the environment. Specific neuronal activity patterns drive long-lasting increases or decreases in the strength of synaptic ...
Adeniyi, Philip A., Ali, Nilufar, Amini, Elham, Blumrich, Eva Maria, Datusalia, Ashok K., Fontanet, Paula, García Romero, Ezra Michelet, Ghosh, Shampa, Golpich, Mojtaba, Hegemann, Regina U., Jain, Vishal, Jamwal, Sumit, Joshi, Pooja, Kushwah, Neetu, Lepeta, Katarzyna, Loke, Hannah, Lourenco, Mychael V., Nawrotek, Katarzyna, Paid, Ramesh K., Pastor, Verónica, Piermartiri, Tetsade, Rotermund, Carola, Saini, Vedangana, Salamian, Ahmad, Schaefer, Natascha, Shahidzadeh, Sheila M., Sharma, Mahima, Sharma, Sorabh, Sinha, Jitendra K., Suárez Pozos, Edna, Turner, Anthony J., Vafadari, Benham, Wilson, Yvette   +32 more
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Nuclear transport factor directs localization of protein synthesis during mitosis [PDF]

Nature Cell Biology, 2009
Export of messenger RNA from the transcription site in the nucleus and mRNA targeting to the translation site in the cytoplasm are key regulatory processes in protein synthesis. In yeast, the mRNA-binding proteins Nab2p and Nab4p/Hrp1p accompany transcripts to their translation site, where the karyopherin Kap104p mediates both their dissociation from ...
Bogaart, G. van den, Meinema, A.C., Krasnikov, V., Veenhoff, L.M., Poolman, B.   +4 more
openaire   +5 more sources

Chemical LTP induces confinement of BDNF mRNA under dendritic spines and BDNF protein accumulation inside the spines

Frontiers in Molecular Neuroscience
The neurotrophin brain-derived neurotrophic factor (BDNF) plays a key role in neuronal development and synaptic plasticity. The discovery that BDNF mRNA can be transported in neuronal dendrites in an activity-dependent manner has suggested that its local
Giorgia Bimbi, Enrico Tongiorgi
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Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

Nature Communications, 2023
The neuronal RNA-binding protein Ptbp2 regulates neuronal differentiation by modulating alternative splicing programs in the nucleus. Such programs contribute to axonogenesis by adjusting the levels of protein isoforms involved in axon growth and ...
Saeede Salehi, Abdolhossein Zare, Gianluca Prezza, Jakob Bader, Cornelius Schneider, Utz Fischer, Felix Meissner, Matthias Mann, Michael Briese, Michael Sendtner   +9 more
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Local Translation in Nervous System Pathologies

Frontiers in Integrative Neuroscience, 2021
Dendrites and axons can extend dozens to hundreds of centimeters away from the cell body so that a single neuron can sense and respond to thousands of stimuli.
María Gamarra, María Gamarra, Aida de la Cruz, Aida de la Cruz, Maite Blanco-Urrejola, Maite Blanco-Urrejola, Maite Blanco-Urrejola, Jimena Baleriola, Jimena Baleriola, Jimena Baleriola   +9 more
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