Results 101 to 110 of about 8,380,026 (270)

Assesment of angiogenesis in basal cell carcinoma using CD31 &CD34 markers and relation with tumor invasiveness in histology [PDF]

Background & Objective : Tumor angiogenesis is essential for tumor growth and appears to play an importating role both in invasive growth and metastasis.
صفايی, زهرا, حديثی, مهدی, فتحي, سولماز, امانی, فیروز   +3 more
core  

Supplementary material for the brief report titled ''Efficacy and Safety of Vismodegib for Locally Advanced Basal Cell Carcinoma: Nine-Year Outcomes from 133 Individually Treated Patients.''

Supplementary material for the brief report titled ''Efficacy and Safety of Vismodegib for Locally Advanced Basal Cell Carcinoma: Nine-Year Outcomes from 133 Individually Treated Patients.'
Chaitidis, Nikolaos
core   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

Advanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici, Mike Bismuth, Meir Goldsmith, Dan Peer, Tali Ilovitsh   +4 more
wiley   +1 more source

Locally advanced basal cell carcinoma in real life: Analysis of a cohort of 452 patients treated with systemic therapy from the CARADERM database

EJC Skin Cancer
Background: Locally advanced basal cell carcinoma (LaBCC) is a challenging condition. The European Association for Dermato-Oncology (EADO) suggested the classification of laBCC into 5 groups.
F. Herms, M. Djermane, M. Beylot-Barry, C. Chaffaut, S. Dalac, O. Dereure, J.J. Grob, L. Mortier, J. Lambert, N. Basset-Seguin   +9 more
doaj   +1 more source

Hedgehog Pathway Inhibitors and Their Utility in Basal Cell Carcinoma: A Comprehensive Review of Current Evidence

Dermatology and Therapy, 2018
Basal cell carcinoma (BCC) is the most commonly diagnosed malignancy in humans, and as such it poses a significant healthcare burden. The majority of BCC cases are amenable to cure by surgical extirpation.
Evelyn Yu-Xin Tay, Yee-Leng Teoh, Matthew Sze-Wei Yeo   +2 more
doaj   +1 more source

Advanced basal cell carcinomas appear preferentially on the scalp of patients with Basal Cell Carcinoma Nevus Syndrome [PDF]

, 2016
Basal Cell Carcinoma Nevus Syndrome is a rare condition in which patients need to meet certain major or minor diagnostic criteria or test positive for chromosome 9 or PTCH1 mutations to be diagnosed.
Updyke, Katelyn, Solomon, James A, Urso, Brittany, Urso, Brittany ; Updyke, Katelyn ; Solomon, James A, Brittany Urso, James A Solomon, Katelyn Updyke   +6 more
core   +1 more source

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

Advanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan, Yuting Shen, Xiaodong Hou, Fengshan Jin, Shaoyue Li, Weichen Xu, Weiwei Ren, Xiaowan Bo, Qiuyan Li, Shuo Liu, Weifan Hao, Chengzhong Peng, Huixiong Xu, Liping Sun, Wenwen Yue   +14 more
wiley   +1 more source

Immunotherapy for locally advanced and metastatic basal cell carcinoma: a narrative review

Translational Cancer Research
Basal cell carcinoma (BCC) is the most common malignancy of humankind, characterized by its low propensity for metastasis and its high recurrence rate. Surgical intervention is the predominant therapeutic approach. However, for cases of locally advanced BCC (laBCC) and metastatic BCC (mBCC), systematic therapy may be the first option.
Li, Xiaoqing, Wang, Hongru, Lu, Qingli
openaire   +2 more sources

Reflectance confocal microscopy identification of subclinical basal cell carcinomas during and after vismodegib treatment

, 2017
Recently, it has been shown that reflectance confocal microscopy (RCM) could identify subclinical basal cell carcinoma (BCC) during vismodegib treatment of locally advanced ...
P. Vercherin, P. Rubegni, Labeille, B, E. Cinotti, Vercherin, P, Cambazard, F, F. Cambazard, Cinotti, E, Couzan, C, B. Labeille, J.L. Perrot, Rubegni, P, Perrot, J L, C. Couzan   +13 more
core   +1 more source