Results 31 to 40 of about 5,418,708 (164)

Clinical Implementation and Perioperative Outcomes of Robot‐Assisted Pelvic Exenteration for Primary Rectal Cancer: A Multicenter Japanese Experience

Annals of Gastroenterological Surgery, EarlyView.
Robot‐assisted pelvic exenteration (RPE) was performed with acceptable perioperative outcomes in selected patients with primary rectal cancer. It may serve as a complementary approach at institutions with sufficient experience in PE, whereas open surgery remains essential for extensive or technically demanding disease.
Shoma Yamamoto, Hiroyasu Kagawa, Yusuke Yatabe, Yusuke Kinugasa   +3 more
wiley   +1 more source

Recent advances in the treatment and outcome of locally advanced rectal cancer

, 2015
Objective To compare the outcomes of treatment of locally advanced rectal cancer of the early era (1975–1990) with those of the late era (1991–1997).
Abdalla, Eddie, Mendenhall, William, Marsh, Robert, Kubilis, Paul, Bray, Elizabeth, Zlotecki, Robert, Copeland III, Edward, Lauwers, Gregory, Solorzano, Carmen, Freeman, Mark, Vauthey, Nicolas   +10 more
core   +1 more source

Long‐Term Prognosis, Residual Recurrence Risk, and Postoperative Management After Pathological Complete Response in Rectal Cancer

Cancer Nexus, EarlyView.
This graphical abstract summarizes the post‐pCR clinical pathway in locally advanced rectal cancer. After neoadjuvant radiotherapy and systemic therapy followed by surgery, patients achieving pCR (ypT0N0) generally have durable disease control, although residual risks of local and distant recurrence remain. Risk assessment, guideline‐based surveillance,
Jia‐ang Wang, Yingjiang Ye, Zhidong Gao, Sen Hou   +3 more
wiley   +1 more source

Visualization of Scattered Tumor Regression Following Neoadjuvant Chemoimmunotherapy With a Novel Intraoperative PET/CT Scanner

Head &Neck, EarlyView.
ABSTRACT Background Neoadjuvant chemoimmunotherapy is being explored in locally advanced head and neck squamous cell carcinoma (HNSCC), yet the spatial patterns of pathologic response and clinical implications remain poorly characterized. Methods A 79‐year‐old female with recurrent left oral tongue SCC (PD‐L122C3 Combined Positive Score 90) who ...
Andreja Radevic, Joaquin Austerlitz, Ashtyn McAdoo, Kyrionna Golliday, Takeshi Takahashi, Mitra Mehrad, Adam J. Rosenberg, Barbara A. Murphy, Eben Rosenthal, Michael C. Topf   +9 more
wiley   +1 more source

Volumetric modulated arc therapy with simultaneous integrated boost for locally advanced rectal cancer

, 2012
To report the feasibility of volumetric modulated arc therapy (VMAT) for neoadjuvant radiotherapy in locally advanced rectal cancer in a dose-escalation protocol and simultaneous integrated boost (SIB) approach.
Deodato F, V. Picardi, M. Massaccesi, Digesù C, A. Piermattei, Piermattei, Angelo, Cilla, Savino, Morganti, Alessio Giuseppe, Picardi, Vincenzo, Caravatta, Luciana, Caravatta L, Macchia, Gabriella, Digesu', Cinzia, Picardi V, Massaccesi, Mariangela, Macchia G, Cilla S, D. Sabatino, Sabatino D, Deodato, Francesco, G. Macchia, S. Cilla, A.G. Morganti, De Spirito M, M. De Spirito, Sabatino, Domenico, De Spirito, Marco, C. Digesù, Massaccesi M, Piermattei A, L. Caravatta, F. Deodato   +31 more
core   +1 more source

Contemporary management of locally advanced rectal cancer: Resolving issues, controversies and shifting paradigms [PDF]

, 2018
Advancements in rectal cancer treatment have resulted in improvement only in locoregional control and have failed to address distant relapse, which is the predominant mode of treatment failure in rectal cancer.
김남규
core   +1 more source

Pelvic Exenteration for Recurrent Rectal Cancer: A Single Institution Experience

, 2021
Aim:Rectal cancer is an important cause of cancer-related deaths worldwide (1-2). Although rectal cancers can be diagnosed earlier nowadays due to the development of screening programmes, 18% of patients have a locally advanced stage at the time of ...
Lütfi Doğan, Mahmut Onur Kültüroğlu, Cemil Yüksel, Eda Güner, Bülent Aksel, Serdar Culcu, Fatih Göksel   +6 more
core   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source