Results 161 to 170 of about 52,640 (225)

Frequency‐Dependent Effects of Transauricular Vagus Nerve Stimulation on Alleviating Visceral Hypersensitivity: Involvement of the Nesfatin‐1/CRF/CRF1R Pathway

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
taVNS alleviates visceral hypersensitivity in a frequency‐dependent manner (2 Hz most effective), potentially via the hypothalamic nesfatin‐1/CRF/CRF1R pathway. ABSTRACT Background Visceral hypersensitivity (VH) is acknowledged as a critical pathogenic mechanism underlying functional gastrointestinal disorders (FGIDs), which is influenced by ...
Wanli Xu, Ziqin Zhou, Shuai Zhou, Ruirui Zhao, Weijian Zhu, Huan Chen, Jingzhu Zhou, Zhaohui Zhang   +7 more
wiley   +1 more source

Brain Changes Underlying Irritable Bowel Syndrome Symptom Improvement in Response to Mindfulness‐Based Stress Reduction

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
Mindfulness‐based stress reduction improves IBS symptoms by changing communication between brain regions at rest. ABSTRACT Background Although the efficacy of mindfulness‐based interventions for improvements in IBS symptoms has been demonstrated, the specific neural mechanisms contributing to these changes remain unclear.
Jennifer S. Labus, Guistinna Tun, Paul W. Savoca, Desiree R. Delgadillo, Kevin Antony, Cathy Liu, Suzanne R. Smith, J. Greg Serpa, Jean Stains, Bruce Naliboff, Kirsten Tillisch   +10 more
wiley   +1 more source

Locus coeruleus alterations in dementia with Lewy bodies: A systematic review. [PDF]

Alzheimers Dement (N Y)
Bain A, Tomeo C, André C, Garnier-Crussard A, de Flores R, Dautricourt S.   +5 more
europepmc   +1 more source

Pulsed taVNS‐Elicited Pupil Dilation: Effects of Intermixed Stimulation, Sham Location, and Respiratory Phase

Psychophysiology, Volume 63, Issue 4, April 2026.
ABSTRACT Transcutaneous auricular vagus nerve stimulation (taVNS) may offer a powerful, noninvasive way to stimulate activity of brainstem arousal systems, including the locus coeruleus–norepinephrine (LC–NE) system. Pulsed taVNS is known to elicit pupil dilation, a marker of LC activity.
Martin Kolnes, Sander Nieuwenhuis
wiley   +1 more source

Greater locus coeruleus vulnerability in atypical clinicopathologic forms of Alzheimer's disease. [PDF]

Alzheimers Dement
Dunlop SR, Matchett BJ, Mannsbart AF, Al-Shaikh FSH, Peng Z, Rothberg DM, Tranovich JF, Duara R, Uribe IV, Gondrez J, Carter RE, Ferman TJ, Day GS, Graff-Radford NR, Dickson DW, Grinberg LT, Murray ME.   +16 more
europepmc   +1 more source

Isometric handgrip contraction increases tibialis anterior intrinsic motoneuron excitability in a dose‐dependent manner

Experimental Physiology, Volume 111, Issue 4, Page 2200-2213, 1 April 2026.
Abstract The contribution of persistent inward currents (PICs) to motoneuron firing in the lower limb typically increases after a remote handgrip contraction, believed to result from diffuse serotonergic input increases in spinal cord. We investigated whether handgrip contraction intensity, duration and/or impulse would affect PIC estimates in tibialis
Lucas Ugliara, Lucas B. R. Orssatto, Amilton Vieira, Gabriel S. Trajano   +3 more
wiley   +1 more source

Effects of vagal nerve stimulation on pain frequency and intensity in chronic migraine in adults: A randomized controlled trial

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract To determine the effects of noninvasive vagal nerve stimulation (nVNS) on the frequency, intensity, impact, and quality of life in individuals with chronic migraine. The randomized controlled trial (RCT) was conducted over 128 participants, randomly assigned to either the experimental or control group.
Rabia Nasir, Mirza Obaid Baig, Turki Abualait, Sumaiyah Obaid, Irij Javed Jadoon, Fawaz Al‐hussain, Shahid Bashir   +6 more
wiley   +1 more source

Neural Circuit Connections and Functions of Locus Coeruleus-Norepinephrine System. [PDF]

Int J Mol Sci
Hao M, Li F, Duan JW, Han MH.
europepmc   +1 more source

Altered locus coeruleus links to atrophy and hypometabolism in individuals with high Alzheimer's disease biomarkers. [PDF]

Alzheimers Dement
Foyard E, Blanchard T, Landeau B, Chauveau L, Naveau M, Poisnel G, Bui E, Chetelat G, de Flores R, Medit‐Ageing Research Group.   +9 more
europepmc   +1 more source

Female-biased astrocytic priming shapes early locus coeruleus vulnerability in an Aβ oligomer milieu. [PDF]

Alzheimers Dement
Kushwaha S, Roy Choudhury R, Bhat P, Kumaran SS, Karunakaran S.   +4 more
europepmc   +1 more source