Results 141 to 150 of about 411,191 (267)

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels

Alzheimer's & Dementia, 2019
This study aimed to assess how interindividual differences in locus coeruleus (LC) magnetic resonance imaging (MRI) contrast relate to cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD).
M. Betts, A. Cárdenas-Blanco, M. Kanowski, A. Spottke, S. Teipel, I. Kilimann, F. Jessen, E. Düzel   +7 more
semanticscholar   +1 more source

Female Mice Show Stronger Time‐of‐Day Modulation of Astrocytic Ca2+ Activity in the Sleep‐Regulatory Ventrolateral Preoptic Nucleus

Glia, Volume 74, Issue 8, August 2026.
VLPO astrocytes exhibit sex‐specific Ca2+ dynamics across the nycthemeral cycle. Males show faster Ca2+ kinetics, while females display increased amplitude, frequency, and network coupling at Zeitgeber Time (ZT)‐14. Sex is a key variable in astrocyte‐based sleep regulation mechanisms.
Félix Camille Bellier, Lou Zonca, David Holcman, Frédéric Chauveau, Nathalie Rouach, Armelle Rancillac   +5 more
wiley   +1 more source

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [18F]‐SMBT‐1 Positron‐Emission Tomography

Glia, Volume 74, Issue 8, August 2026.
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford, James W. M. Kang, OIivia I. Davanzo, Hyunsol Lim, Sabrina Salberg, Marissa Srgo, Crystal Li, Gaelle M. Emvalomenos, Bianca Jupp, Matthew Long, Wayne Noonan, Mohammad B. Haskali, Richelle Mychasiuk, Kevin A. Keay, Luke A. Henderson   +14 more
wiley   +1 more source

Corticotropin-Releasing Factor in the Norepinephrine Nucleus, Locus Coeruleus, Facilitates Behavioral Flexibility [PDF]

, 2012
Corticotropin-releasing factor (CRF), the stress-related neuropeptide, acts as a neurotransmitter in the brain norepinephrine nucleus, locus coeruleus (LC), to activate this system during stress.
Han, Rebecca, Wang, Wei-Wen, McFadden, Kile, Snyder, Kevin, Valentino, RJ (reprint author), Childrens Hosp Philadelphia, Abramson Pediat Res Ctr 402D, Dept Anesthesiol & Crit Care Med, Philadelphia, PA 19104 USA., Valentino, Rita J.   +5 more
core  

Combining electroacupuncture and transcutaneous electrical acupoint stimulation for psychiatric disorders in women victims of domestic violence: An assessor‐blinded, randomised controlled trial

General Psychiatry, Volume 39, Issue 4, August 2026.
ABSTRACT Background Women victims of domestic violence often present with psychiatric disorders and may benefit from nonpharmacological interventions. Acupoint stimulation therapy may be an effective approach. Aims To examine whether a combination of electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS) can alleviate ...
Sichang Yang, Wai Chun Mok, Denise Shuk Ting Cheung, Agnes Tiwari, Calvin Pak Wing Cheng, Haiyong Chen, Zongshi Qin, Mei Yan Chan, Xiaoru Hu, Kam Chi Yu, Pui Yan Chan, Wenqi Li, Sheng‐Nan Liu, Min‐Qing Gu, Xinjing Yang, Doris Lee, Sai Ho Sin, Zhang‐Jin Zhang   +17 more
wiley   +1 more source

Complex Regional Pain Syndrome: Why Does Pain Spread From the Injured Limb to the Face? [PDF]

, 2009
In patients with complex regional pain syndrome (CRPS), sensory disturbances commonly spread outside the affected limb, in particular hemilaterally. Hyperalgesia to pressure-pain was, for instance, documented in the forehead ipsilateral to the affected ...
Knudsen, Lone
core   +1 more source

Mapping Neurodegenerative Changes in Clinically Uncertain Parkinsonian Syndrome Patients Using Fast MR Spin TomogrAphy in Time‐Domain (MR‐STAT) Relaxometry at 3T

Journal of Magnetic Resonance Imaging, Volume 64, Issue 2, Page 429-439, August 2026.
ABSTRACT Background MR Spin TomogrAphy in Time‐domain (MR‐STAT) enables accelerated multiparametric relaxometry (T1/T2). Previous relaxometry studies predominantly compared Parkinson's disease patients with healthy controls (HC). The potential of relaxometry to distinguish neurodegenerative from non‐neurodegenerative parkinsonism in clinically ...
Martin B. Schilder, Elon D. Wallert, Stefano Mandija, Oscar van der Heide, Hongyan Liu, Miha Fuderer, Edwin Versteeg, Jan Booij, Rob M. A. de Bie, Martijn Beudel, Henk W. Berendse, Tom van Mierlo, Jeroen Blankevoort, Cornelis A. T. van den Berg, Elsmarieke van de Giessen, Alessandro Sbrizzi   +15 more
wiley   +1 more source

Pharmacological Influences on the R2 Blink Reflex Response in Healthy Participants: A Systematic Review

European Journal of Neuroscience, Volume 64, Issue 3, August 2026.
Pharmacological modulation of the R2 blink reflex was comparable whether responses were elicited using standard patch or concentric electrodes. Across nine studies, noradrenergic and GABAergic interventions produced the most consistent effects, supporting the R2 blink reflex as a sensitive biomarker of trigeminofacial nociceptive processing.
Josh Murphy, Joy Krecke, Celia Morgan, Paul H. Strutton, Kirsty Bannister, Sam W. Hughes   +5 more
wiley   +1 more source

Hippocampus and locus coeruleus activity on rats chronically treated with diazepam [PDF]

, 2001
The neural mechanisms underlying benzodiazepine (BZD) dependence remain equivocal. The present studies tested the hypothesis that similar neural circuitry might be involved in the effects of chronic 7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepine-2(1H ...
Nasif, Fernando J., Fernando J Nasif, Gerardo R Marchesini, Pérez, Mariela F., Marchesini, Gerardo R., Maglio, Laura E., Ramírez, Oscar A., Laura E Maglio, Mariela F Pérez, Oscar A Ramirez   +9 more
core   +1 more source