Results 131 to 140 of about 411,191 (267)

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin, Kinga Igloi, Alison Montagrin, Samika Kumar, Jeremy Hofmeister, Markus Gschwind, Sophie Schwartz, Virginie Sterpenich   +7 more
wiley   +1 more source

Comparing the Effect of Microinjection of Angiotensin II and Captopril to the Locus Coeruleus on Morphine Withdrawal Signs in Rat

مجله دانشکده پزشکی اصفهان, 2009
Background: Locus coeruleus is one of important involved sites in morphine withdrawal signs, contains high densities of Angiotensin II receptor binding sites.
Zohreh Azizolahi, Hojatollah Alaei, Mahmoud Hosseini, Ali Asghar Pilehvarian   +3 more
doaj  

Neuroinflammation and noradrenergic modulation with β2-adrenoceptors: Emerging therapeutic targets for Parkinson’s diseases

Neural Regeneration Research
Neurodegenerative disorders, such as Parkinson’s disease, are strongly influenced by neuroinflammatory processes and dysfunction of the locus coeruleus-noradrenergic system.
Maria Micaelle Gomes Tavares, Milena Caroline Nunes Monteiro de Carvalho, Mylaine Santos Mendonça, Iasmin de Carvalho Dantas, Katty Anne Amador de Lucena Medeiros, José Ronaldo dos Santos, Auderlan Mendonça de Gois   +6 more
doaj   +1 more source

Impaired Alertness Correlates With Chronic Anxiety: A Prospective Tertiary University Centre Cohort

Journal of Sleep Research, EarlyView.
ABSTRACT The Maintenance of Wakefulness Test (MWT) is a widely used objective measure of daytime alertness, especially in patients with sleep disorders at increased risk of accidents. Anxiety and depression are common in this population and may influence subjective sleepiness and objective alertness.
Anice Borjon, Lucie Bobin, François Ricordeau, Lucas Marces, Hugo Fornelli, Thierry Petitjean, Amandine Viccica, Elena Charbonnier, Emeric Stauffer, Barbara Charbotel, Jacques Taillard, Renaud Tamisier, Laure Peter‐Derex, Pierre Tankéré   +13 more
wiley   +1 more source

Fully automated MRI‐based analysis of the locus coeruleus in aging and Alzheimer's disease dementia using ELSI‐Net

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION The locus coeruleus (LC) is linked to the development and pathophysiology of neurodegenerative diseases such as Alzheimer's disease (AD).
Max Dünnwald, Friedrich Krohn, Alessandro Sciarra, Mousumi Sarkar, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Annika Spottke, Johanna Brustkern, Michael T. Heneka, Frederic Brosseron, Falk Lüsebrink, Dorothea Hämmerer, Emrah Düzel, Klaus Tönnies, Steffen Oeltze‐Jafra, Matthew J. Betts   +23 more
doaj   +1 more source

Locus Coeruleus-Norepinephrine System: Spheres of Influence and Contribution to the Development of Neurodegenerative Diseases

Frontiers in Bioscience-Landmark
Locus coeruleus is a small bilateral nucleus in the brainstem. It is the main source of norepinephrine (noradrenaline) throughout the central nervous system (about 70% of all norepinephrine in the central nervous system), and, as shown in numerous ...
Vladimir Nikolaevich Nikolenko, Irina Dmitriyevna Borminskaya, Arina Timofeevna Nikitina, Maria Sergeevna Golyshkina, Negoriya Aliagayevna Rizaeva, Marine Valikovna Oganesyan   +5 more
doaj   +1 more source

All Is Relative—A Call for Considering “Physiologically Informed” Control Conditions to Improve the Mechanistic Understanding of the Effects of Physical Exercise on Cognition

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT There is a growing interest in elucidating the mechanisms that drive the benefits of physical exercise on cognitive performance. A key element for a better understanding of a particular phenomenon (e.g., the mediators of the exercise‐cognition interaction) is the selection of an appropriate control condition/group as the basis for causal ...
Fabian Herold, Benjamin Tari, Sylwester Kujach, Olivier Dupuy, C. Shawn Green, Thomas Gronwald, Matthew Heath   +6 more
wiley   +1 more source

Modulating cortical excitability and cortical arousal by pupil self-regulation

Nature Communications
The brain’s arousal state (i.e., central arousal) is regulated by multiple neuromodulatory nuclei in the brainstem and significantly influences high-level cognitive processes.
Marieke Lieve Weijs, Silvia Missura, Weronika Potok-Szybińska, Marc Bächinger, Bianca Badii, Manuel Carro-Domínguez, Nicole Wenderoth, Sarah Nadine Meissner   +7 more
doaj   +1 more source

Locus Coeruleus-Norepinephrine Modulation of Sensory Processing and Perception: A Focused Review

Neuroscience and Biobehavioral Reviews, 2019
The locus coeruleus-norepinephrine (LC-NE) system is involved in many brain functions and neurological disorders. In this review we discuss how LC-NE signaling affects the activity of cortical and subcortical sensory neurons, and how it influences ...
Jim McBurney-Lin, Ju Lu, Yi Zuo, Hongdian Yang   +3 more
semanticscholar   +1 more source

The locus coeruleus

Alzheimer’s disease is a common form of dementia that impairs memory and thinking, usually later in life. Years before symptoms appear, harmful proteins start to build up in the brain. This early phase, called the preclinical stage, offers an opportunity to detect and address the disease before significant damage occurs.
openaire   +2 more sources