Results 111 to 120 of about 411,191 (267)
Journal of Anatomy, EarlyView.The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva +19 more
wiley +1 more source
The Locus coeruleus in Parkinson’s disease - from basic research to new translational perspectives - [PDF]
, 2019 This cumulative dissertation summarizes three peer-reviewed publications addressing different aspects of the prodromal and manifest phase of Parkinson’s disease with special emphasis on the vulnerability of the noradrenergic locus coeruleus.
Henrich, Martin Timo +1 more
core +3 more sources
ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus
Cell Reports, 2019 Summary: Patients with germline mutations in the urea-cycle enzyme argininosuccinate lyase (ASL) are at risk for developing neurobehavioral and cognitive deficits. We find that ASL is prominently expressed in the nucleus locus coeruleus (LC), the central
Shaul Lerner +34 more
doaj +1 more source
A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian multiple system atrophy
BMC Neurology, 2020 Background Parkinsonian variant of multiple system atrophy is a neurodegenerative disorder frequently misdiagnosed as Parkinson’s disease. No early imaging biomarkers currently differentiate these disorders.
Rita Moiron Simões +12 more
doaj +1 more source
Nature Human Behaviour, 2019 For decades, research into memory decline in human cognitive ageing has focused on neocortical regions, the hippocampus and dopaminergic neuromodulation.
M. Dahl +6 more
semanticscholar +1 more source
A Role for the Locus Coeruleus in the Modulation of Feeding [PDF]
, 2019 Abstract Recent data suggest that LC-NE neurons play a role in fear-induced suppression of feeding, but their endogenous activity in naturally behaving animals has not been explored. We found that endogenous activity of LC-NE neurons was enhanced during food approach and suppressed during food consumption, and that these food-evoked LC ...
Natale R. Sciolino +16 more
openaire +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population. Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic and mental illness, especially depression and anxiety disorders.
Dieter Riemann +13 more
wiley +1 more source
Effect of sensory deprivation and Locus Coeruleus (LC) electrical stimulation on the response properties of layer IV barrel cortex neurons in male rats [PDF]
Introduction: Barrel cortex of rodents is responsible for sensory information processing from muzzle whiskers. Locus coeruleus (LC) as the main source of norepinephrine (NE) in the cortex, is effective on the sensory information processing. Methods:
شمسی زاده, علی +4 more
core
Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus
Cell Reports, 2018 Summary: Preclinical work has long focused on male animals, though biological sex clearly influences risk for certain diseases, including many psychiatric disorders.
Bernard Mulvey +8 more
doaj +1 more source
In vivo visualization of age-related differences in the locus coeruleus
Neurobiology of Aging, 2019 The locus coeruleus (LC), the major origin of noradrenergic modulation of the central nervous system, may play an important role in neuropsychiatric disorders including Parkinson's disease and Alzheimer's disease. The pattern of age-related change of the
Kathy Y. Liu +10 more
semanticscholar +1 more source