Results 101 to 110 of about 380,424 (246)

Complex Regional Pain Syndrome: Why Does Pain Spread From the Injured Limb to the Face? [PDF]

open access: yes, 2009
In patients with complex regional pain syndrome (CRPS), sensory disturbances commonly spread outside the affected limb, in particular hemilaterally. Hyperalgesia to pressure-pain was, for instance, documented in the forehead ipsilateral to the affected ...
Knudsen, Lone
core  

The Role of the Antidepressants in Managing Chemotherapy‐Induced Neuropathic Pain: A Systematic Review

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From symptom relief to multimodal care: duloxetine and amitriptyline may reduce established CIPN‐related pain and provide a therapeutic foundation for future combination strategies. ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and debilitating complication of cancer treatment, characterized by neuropathic pain, sensory ...
Rosamaria Caminiti   +13 more
wiley   +1 more source

Nurses' Visual Attention During Initial Observation of Patients With Suspected Pneumonia: An Observational Pupillometry Study

open access: yesJapan Journal of Nursing Science, Volume 23, Issue 4, October 2026.
ABSTRACT Aim Observation requires selective attention to visual information acquired through gaze. Measuring pupil diameter, an index of attention, we examined skilled and novice nurses during the initial assessment of a patient urgently admitted with suspected community‐acquired pneumonia.
Shoya Kamijo   +3 more
wiley   +1 more source

All Is Relative—A Call for Considering “Physiologically Informed” Control Conditions to Improve the Mechanistic Understanding of the Effects of Physical Exercise on Cognition

open access: yesScandinavian Journal of Psychology, Volume 67, Issue 5, Page 1246-1266, October 2026.
ABSTRACT There is a growing interest in elucidating the mechanisms that drive the benefits of physical exercise on cognitive performance. A key element for a better understanding of a particular phenomenon (e.g., the mediators of the exercise‐cognition interaction) is the selection of an appropriate control condition/group as the basis for causal ...
Fabian Herold   +6 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1842-1850, September 2026.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Natural Locus Coeruleus Dynamics During Feeding

open access: yes
Data and code for the manuscript "Natural Locus Coeruleus Dynamics During Feeding" by Sciolino et.
SCIOLINO, NATALE
core   +1 more source

Locus coeruleus stimulation by corticotropin-releasing hormone suppresses in vitro cellular immune responses

open access: yes, 1994
Previous studies have demonstrated that stressors alter cellular immune system function, and increase the activity of locus coeruleus neurons. Furthermore, stressors increase the release of corticotropin-releasing hormone (CRH) and locus coeruleus ...
S Rassnick, BS Rabin, AF Sved
core   +1 more source

Are infraslow oscillations the missing link between sleep and Alzheimer's?

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Locus coeruleus (LC) and glymphatic dysfunction have been linked both to Alzheimer's disease (AD) and, recently, to infraslow oscillation (ISO) in sleep spindle (sigma) activity (ISO). Here we hypothesize ISO integrity is a critical link between sleep and AD.
Demetrio Grollero   +6 more
wiley   +1 more source

Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity

open access: yeseLife
Impairments of locus coeruleus (LC) are implicated in anxiety/depression and Alzheimer’s disease (AD). Increases in cytosolic noradrenaline (NA) concentration and monoamine oxidase A (MAO-A) activity initiate the LC impairment through production of NA ...
Hiroki Toyoda   +6 more
doaj   +1 more source

Tau‐associated neuronal loss in the intermediate nucleus of the human hypothalamus, a putative VLPO analog, in progressive supranuclear palsy and Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract BACKGROUND Sleep phenotypes differ in progressive supranuclear palsy (PSP) and Alzheimer's disease (AD). The human intermediate nucleus (IntN), a putative ventrolateral preoptic analog, promotes non‐rapid eye movement (NREM) sleep, but its disease‐specific vulnerability is unclear. METHODS Post mortem hypothalami (n = 30; baseline [Braak stage
Shima Rastegar‐Pouyani   +14 more
wiley   +1 more source

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