Results 101 to 110 of about 411,191 (267)
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, EarlyView.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Role of the locus coeruleus arousal system in cognitive control
Journal of neuroendocrinology, 2020 Cognitive control lies at the core of human adaptive behaviour. Humans vary substantially in their ability to execute cognitive control with respect to optimally facing environmental challenges, although the neural origins of this heterogeneity are ...
M. Grueschow, Birgit Kleim, C. Ruff
semanticscholar +1 more source
The Locus Coeruleus in Chronic Pain
International Journal of Molecular SciencesPain perception is the consequence of a complex interplay between activation and inhibition. Noradrenergic pain modulation inhibits nociceptive transmission and pain perception. The main source of norepinephrine (NE) in the central nervous system is the Locus Coeruleus (LC), a small but complex cluster of cells in the pons.
Jorge Castejón España +2 more
openaire +2 more sources
Clinical Obesity, Volume 15, Issue 2, April 2025.Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source
LOCUS COERULEUS NOREPINEPHRINE IN ACTIVE AVOIDANCE AND REWARD SEEKING BEHAVIOR [PDF]
Cue driven behavior relies on the ability to appropriately respond to stimuli in the environment to obtain resources (food, water, etc.) or avoid threats/danger.
Rodberg, Ellen
core +1 more source
Annals of Clinical and Translational Neurology, 2022 There is clear, early noradrenergic dysfunction in Alzheimer's disease. This is likely secondary to pathological tau deposition in the locus coeruleus, the pontine nucleus that produces and releases noradrenaline, prior to involvement of cortical brain ...
Michael David, Paresh A. Malhotra
doaj +1 more source
Journal of Child Psychology and Psychiatry, EarlyView.Background Altered social cognition in autism may be influenced by difficulties in domain‐general functions, such as selective attention. Here, we manipulated the requirement for selective attention during a visual perspective taking (VPT) task and used neurophysiological indices to delineate underlying mechanisms.
Leonie Polzer +7 more
wiley +1 more source
Locus coeruleus syndrome as a complication of tectal surgery [PDF]
, 2015 We describe a case of a 48-year-old woman who underwent a resection of a tectal pilocytic astrocytoma complicated by a sequence of fluctuating consciousness, psychosis with complex hallucinations and lasting sleeping disturbances in which she vividly ...
Kronenburg, Annick +5 more
core +1 more source
Neural Plasticity, 2018 The use of transcranial electrical stimulation (TES) as a method to augment neural activity has increased in popularity in the last decade and a half. The specific application of TES to the left prefrontal cortex has been shown to produce broad cognitive
Matthew S. Sherwood +3 more
doaj +1 more source
Neuron, 2015 SUMMARY Changes in pupil diameter that reflect effort and other cognitive factors are often interpreted in terms of the activity of norepinephrine-containing neurons in the brainstem nucleus locus coeruleus (LC), but there is little direct evidence for ...
S. Joshi, Yin Li, R. Kalwani, J. Gold
semanticscholar +1 more source