Results 101 to 110 of about 52,640 (225)
Journal of Sleep Research, EarlyView.ABSTRACT The mouse sleep is mostly recorded with only epidural electrodes and divided simply into NREM and REM stages. With the help of distributed intracerebral triplet electrodes, we searched for possible new electrophysiological signatures to characterise more specific sleep substages within the timeframe of seconds to tens of minutes.
Nanxiang Jin +8 more
wiley +1 more source
Modulating cortical excitability and cortical arousal by pupil self-regulation
Nature CommunicationsThe brain’s arousal state (i.e., central arousal) is regulated by multiple neuromodulatory nuclei in the brainstem and significantly influences high-level cognitive processes.
Marieke Lieve Weijs +7 more
doaj +1 more source
How Does the Body Affect the Mind? Role of Cardiorespiratory Coherence in the Spectrum of Emotions [PDF]
, 2015 The brain is considered to be the primary generator and regulator of emotions; however, afferent signals originating throughout the body are detected by the autonomic nervous system (ANS) and brainstem, and, in turn, can modulate emotional processes ...
Crawford, Molly W., Ravinder, Jerath
core
Psychiatry and Clinical Neurosciences, EarlyView.Aim Despite being one of the most disabling symptoms of post‐traumatic stress disorder (PTSD)—disrupting sleep continuity, reinforcing hyperarousal, and worsening psychiatric comorbidity—the physiological signature of Trauma‐related nightmares (TRNs) under naturalistic sleep conditions remains poorly characterized.
Dorone Feingold +8 more
wiley +1 more source
Scandinavian Journal of Psychology, EarlyView.ABSTRACT There is a growing interest in elucidating the mechanisms that drive the benefits of physical exercise on cognitive performance. A key element for a better understanding of a particular phenomenon (e.g., the mediators of the exercise‐cognition interaction) is the selection of an appropriate control condition/group as the basis for causal ...
Fabian Herold +6 more
wiley +1 more source
Computational modeling of spike generation in serotonergic neurons of the dorsal raphe nucleu [PDF]
, 2012 We consider here a single-compartment model of these neurons which is capable of describing many of the known features of spike generation, particularly the slow rhythmic pacemaking activity often observed in these cells in a variety of species. Included
Penington, Nicholas J. +1 more
core
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems +5 more
wiley +1 more source
Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1
Annals of Neurology, Volume 99, Issue 5, Page 1173-1178, May 2026.Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan +5 more
wiley +1 more source
Computational Design of Azole Derivatives as Multifunctional Agents for Alzheimer's Disease
Applied Organometallic Chemistry, Volume 40, Issue 5, May 2026.A series of 19 azole derivatives were evaluated using bioinformatic tools and density functional theory in the context of multifunctional agents for Alzheimer's disease and were classified as potential antioxidant, distributor, and suppressor agents. ABSTRACT Alzheimer's disease (AD) is the most common form of dementia, characterized by multifactorial ...
Nicolás Puentes‐Díaz +5 more
wiley +1 more source