Results 81 to 90 of about 380,424 (246)

Double‐blind, sham‐controlled, trial of rhythmic 10 Hz median nerve stimulation for the reduction of tics in Tourette syndrome: Analyses of 3‐month follow‐up data for those receiving active stimulation

Journal of Neuropsychology, EarlyView.
Abstract Tourette syndrome [TS] is a neurological disorder of childhood onset characterised by the occurrence of tics: repetitive, purposeless movements or vocalisations. Effective treatment for tic disorders is an area of considerable unmet clinical need.
Stephen R. Jackson, Barbara Morera Maiquez, Georgina M. Jackson   +2 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Chronic insomnia, REM sleep instability and emotional dysregulation: A pathway to anxiety and depression?

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population. Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic and mental illness, especially depression and anxiety disorders.
Dieter Riemann, Raphael J. Dressle, Fee Benz, Kai Spiegelhalder, Anna F. Johann, Christoph Nissen, Elisabeth Hertenstein, Chiara Baglioni, Laura Palagini, Lukas Krone, Michael L. Perlis, Katharina Domschke, Mathias Berger, Bernd Feige   +13 more
wiley   +1 more source

Locus Coeruleus and Dopamine-Dependent Memory Consolidation

Neural Plasticity, 2017
Most everyday memories including many episodic-like memories that we may form automatically in the hippocampus (HPC) are forgotten, while some of them are retained for a long time by a memory stabilization process, called initial memory consolidation ...
Miwako Yamasaki, Tomonori Takeuchi
doaj   +1 more source

The effects of footshock and immobilization stress on tyrosine hydroxylase phosphorylation in the rat locus coeruleus and adrenal gland

, 2011
Tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis, is regulated acutely by protein phosphorylation. No studies have systematically investigated the time course of TH phosphorylation in vivo in response to different ...
Bobrovskaya, L., L. Guan, Guan, L., L.K. Ong, P.W. Dickson, Dickson, P. W., B. Stutz, Dunkley, P., P.R. Dunkley, Dunkley, P. R., Stutz, B., Ong, L. K., L. Bobrovskaya, Dickson, P., Ong, L.K.   +14 more
core   +1 more source

The futuristic manifolds of REM sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since one of its first descriptions 70 years ago, rapid eye movement sleep has continually inspired and excited new generations of sleep researchers. Despite significant advancements in understanding its neurocircuitry, underlying mechanisms and microstates, many questions regarding its function, especially beyond the early neurodevelopment ...
Liborio Parrino, Ivana Rosenzweig
wiley   +1 more source

Comparing the Effect of Microinjection of Angiotensin II and Captopril to the Locus Coeruleus on Morphine Withdrawal Signs in Rat

مجله دانشکده پزشکی اصفهان, 2009
Background: Locus coeruleus is one of important involved sites in morphine withdrawal signs, contains high densities of Angiotensin II receptor binding sites.
Zohreh Azizolahi, Hojatollah Alaei, Mahmoud Hosseini, Ali Asghar Pilehvarian   +3 more
doaj  

Neuroinflammation and noradrenergic modulation with β2-adrenoceptors: Emerging therapeutic targets for Parkinson’s diseases

Neural Regeneration Research
Neurodegenerative disorders, such as Parkinson’s disease, are strongly influenced by neuroinflammatory processes and dysfunction of the locus coeruleus-noradrenergic system.
Maria Micaelle Gomes Tavares, Milena Caroline Nunes Monteiro de Carvalho, Mylaine Santos Mendonça, Iasmin de Carvalho Dantas, Katty Anne Amador de Lucena Medeiros, José Ronaldo dos Santos, Auderlan Mendonça de Gois   +6 more
doaj   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Nature Communications, 2020
Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.
Kathy Y. Liu, Rogier A. Kievit, Kamen A. Tsvetanov, Matthew J. Betts, Emrah Düzel, James B. Rowe, Cam-CAN, Robert Howard, Dorothea Hämmerer   +8 more
doaj   +1 more source