Results 81 to 90 of about 52,640 (225)

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh, Alhasan Altayf, Ayham Qatza, Abubaker Alghazal, Hasan Al‐sakkaf, Muhammed Elhadi   +5 more
wiley   +1 more source

The "Ram Effect": A "Non-Classical" Mechanism for Inducing LH Surges in Sheep [PDF]

, 2016
During spring sheep do not normally ovulate but exposure to a ram can induce ovulation. In some ewes an LH surge is induced immediately after exposure to a ram thus raising questions about the control of this precocious LH surge.
A Caraty, A Caraty, A Chanvallon, A Chanvallon, AC Gore, AE Herbison, AL Goodman, AM Etgen, Audrey Chanvallon, C Fabre-Nys, C Fabre-Nys, C Fabre-Nys, C Fabre-Nys, CA Barraclough, CE Adams, CE Adams, CH Conaway, CH Wu, CJ Scott, Claude Fabre-Nys, CM Oldham, CS Corker, DE Wildt, DE Wright, DF Hardy, Didier Lomet, DR Lindsay, DT Baird, DT Pearce, E Elias, FJ Karsch, FJ Karsch, GB Martin, GW Montgomery, H Gelez, HG Spies, IJ Clarke, J Bakker, JA Banks, JA Rawson, Joëlle Dupont, JP Signoret, JP Signoret, JP Signoret, JR Day, K Brown-Grant, K Maeda, L Dufy-Barbe, L Xia, Lionel Lardic, M Acosta-Martinez, MJ Baum, MJ Gibson, MS Smith, MX Zarrow, NP Evans, OR Dyrmundsson, P Mauleon, P Richard, Peter J. Hansen, Q Li, R Papay, R Ungerfeld, RD Randel, RE Szawka, Rex J. Scaramuzzi, RJ Scaramuzzi, RL Goodman, RL Goodman, RL Goodman, RL Goodman, RL Hauger, S Ben Saïd, S Yamada, SM Moenter, SP Yang, SP Yang, SP Yang, SR Milligan, SR Milligan, SR Wersinger, Stéphanie Martinet, VD Ramirez, W Jöchle, Y Tillet, Y Tillet   +85 more
core   +9 more sources

Parkinson's disease dementia: a neural networks perspective. [PDF]

, 2015
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to 90% of patients with Parkinson's disease. With increasing life expectancy in western countries, Parkinson's disease dementia is set to become even more ...
Foltynie, T, Gratwicke, J, Jahanshahi, M
core   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia [PDF]

, 2010
of poster presentation shown at the 2nd Biennial Schizophrenia International Research Conference on Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in ...
Dawson, Neil, Higham, Des, Morris, Brian, Pratt, Judith   +3 more
core   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Locus Coeruleus and Dopamine-Dependent Memory Consolidation

Neural Plasticity, 2017
Most everyday memories including many episodic-like memories that we may form automatically in the hippocampus (HPC) are forgotten, while some of them are retained for a long time by a memory stabilization process, called initial memory consolidation ...
Miwako Yamasaki, Tomonori Takeuchi
doaj   +1 more source

Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography [PDF]

, 2012
Preliminary investigation of the radioiodinated (S,S)-reboxetine analogue, 123I-INER, in baboons showed this tracer to have promise for imaging the noradrenaline transporter (NAT) using single photon emission computed tomography (SPECT).
Baldwin, Baldwin, Chang, Ding, Gandelman, Grandoso, Jobson, Jobson, Jobson, Kanegawa, Kiyono, Kung, Lakshmi, McConathy, Schou, Schou, Schou, Seibyl, Seneca, Smith, Stoddart, Tamagnan, Tavares, Tavares, Tejani-Butt, Zeng, Zoghbi   +26 more
core   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Nature Communications, 2020
Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.
Kathy Y. Liu, Rogier A. Kievit, Kamen A. Tsvetanov, Matthew J. Betts, Emrah Düzel, James B. Rowe, Cam-CAN, Robert Howard, Dorothea Hämmerer   +8 more
doaj   +1 more source