Results 81 to 90 of about 411,191 (267)
The Locus Coeruleus Noradrenaline System in Delirium
Frontiers in Aging Neuroscience, 2021 Delirium is a brain state involving severe brain dysfunction affecting cognitive and attentional capacities. Our opinion statement review aims to elucidate the relationship between abnormal arousal and locus coeruleus (LC) activity in cognitive ...
Niels Hansen, Alina Isabel Rediske
doaj +1 more source
Epilepsia Open, EarlyView.The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston +6 more
wiley +1 more source
Bladder distention activates noradrenergic locus coeruleus neurons by an excitatory amino acid mechanism. [PDF]
, 1992 International audienceThe present study was designed to determine the neurotransmitter(s) involved in activation of noradrenergic locus coeruleus neurons by urinary bladder distention.
Aston-Jones, G. +3 more
core +1 more source
Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus
Frontiers in Aging Neuroscience, 2022 Chronic sleep disruption is a risk factor for Alzheimer’s disease (AD), yet mechanisms by which sleep disturbances might promote or exacerbate AD are not understood.
Henry Nick +3 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2023 Noradrenergic projections from the brainstem locus coeruleus drive arousal, attentiveness, mood, and memory, but specific adrenoceptor (AR) function across the varied brain cell types has not been extensively characterized, especially with agonists. This
Rachel A. Matt +5 more
doaj +1 more source
In vivo mapping of the human locus coeruleus [PDF]
NeuroImage, 2009 The locus coeruleus (LC) is a brainstem structure that has widespread cortical and sub-cortical projections to modulate states of attention. Our understanding of the LC's role in both normal attention and clinical populations affected by disrupted attention would be advanced by having in vivo functional and structural markers of the human LC.
Noam I. Keren +4 more
openaire +2 more sources
Tracking Genetic Parkinson's Disease with Molecular Imaging: A Systematic Review
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) is a worldwide, complex neurodegenerative disorder influenced by both genetic and environmental factors. Around 15–20% of PD cases are linked to genetic mutations, providing insights into the disease's pathogenesis.
Chiara Meneghini +5 more
wiley +1 more source
Mouse Locus Coeruleus Noradrenergic Neurons Project [PDF]
, 2021 This data is for ' Chemogenetic Stimulation of Tonic Locus Coeruleus Activity Strengthens the Default Mode Network'.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Hsu, L (via Mendeley Data)
core +1 more source
Communications Biology, 2023 Chemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex.
Zafar Iqbal +7 more
doaj +1 more source