Results 91 to 100 of about 380,424 (246)

Cardiovascular Responses to Natural and Auditory Evoked Slow Waves Predict Post‐Sleep Cardiac Function

Journal of Sleep Research, EarlyView.
ABSTRACT The importance of sleep as a key component of cardiovascular health has been increasingly recognized. Our previous research demonstrated that auditory‐enhanced slow waves increase cardiac function, but the underlying mechanisms behind these beneficial effects remain uncertain. In this study, we examined the influence of two types of slow waves
Giulia Alessandrelli, Stephanie Huwiler, Giulio Bernardi, Manuel Carro‐Domínguez, Fabia Stich, Rossella Sala, Florent Aziri, Anna Trippel, Susanne Markendorf, David Niederseer, Philipp Bohm, Pietro Cerveri, Francesca Siclari, Reto Huber, Nicole Wenderoth, Christian Schmied, Caroline Lustenberger   +16 more
wiley   +1 more source

Fully automated MRI‐based analysis of the locus coeruleus in aging and Alzheimer's disease dementia using ELSI‐Net

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION The locus coeruleus (LC) is linked to the development and pathophysiology of neurodegenerative diseases such as Alzheimer's disease (AD).
Max Dünnwald, Friedrich Krohn, Alessandro Sciarra, Mousumi Sarkar, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Annika Spottke, Johanna Brustkern, Michael T. Heneka, Frederic Brosseron, Falk Lüsebrink, Dorothea Hämmerer, Emrah Düzel, Klaus Tönnies, Steffen Oeltze‐Jafra, Matthew J. Betts   +23 more
doaj   +1 more source

Locus Coeruleus-Norepinephrine System: Spheres of Influence and Contribution to the Development of Neurodegenerative Diseases

Frontiers in Bioscience-Landmark
Locus coeruleus is a small bilateral nucleus in the brainstem. It is the main source of norepinephrine (noradrenaline) throughout the central nervous system (about 70% of all norepinephrine in the central nervous system), and, as shown in numerous ...
Vladimir Nikolaevich Nikolenko, Irina Dmitriyevna Borminskaya, Arina Timofeevna Nikitina, Maria Sergeevna Golyshkina, Negoriya Aliagayevna Rizaeva, Marine Valikovna Oganesyan   +5 more
doaj   +1 more source

The locus coeruleus

Alzheimer’s disease is a common form of dementia that impairs memory and thinking, usually later in life. Years before symptoms appear, harmful proteins start to build up in the brain. This early phase, called the preclinical stage, offers an opportunity to detect and address the disease before significant damage occurs.
openaire   +2 more sources

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin, Kinga Igloi, Alison Montagrin, Samika Kumar, Jeremy Hofmeister, Markus Gschwind, Sophie Schwartz, Virginie Sterpenich   +7 more
wiley   +1 more source

Modulating cortical excitability and cortical arousal by pupil self-regulation

Nature Communications
The brain’s arousal state (i.e., central arousal) is regulated by multiple neuromodulatory nuclei in the brainstem and significantly influences high-level cognitive processes.
Marieke Lieve Weijs, Silvia Missura, Weronika Potok-Szybińska, Marc Bächinger, Bianca Badii, Manuel Carro-Domínguez, Nicole Wenderoth, Sarah Nadine Meissner   +7 more
doaj   +1 more source

The Relationship Between Resting State Quantitative EEG and Daytime Sleepiness Complaints in Parkinson's Disease

Journal of Sleep Research, EarlyView.
ABSTRACT Although many studies have reported the presence of daytime sleepiness in Parkinson's disease (PD), either a weak or no association has been found between self‐reported and current objective measures of daytime sleepiness in this population. Changes in resting state quantitative electroencephalography (qEEG) have been associated with increased
Thaïna Rosinvil, Ronald B. Postuma, Jean‐Marc Lina, Jacques Montplaisir, Jean‐François Gagnon, Julie Carrier   +5 more
wiley   +1 more source

Impaired Alertness Correlates With Chronic Anxiety: A Prospective Tertiary University Centre Cohort

Journal of Sleep Research, EarlyView.
ABSTRACT The Maintenance of Wakefulness Test (MWT) is a widely used objective measure of daytime alertness, especially in patients with sleep disorders at increased risk of accidents. Anxiety and depression are common in this population and may influence subjective sleepiness and objective alertness.
Anice Borjon, Lucie Bobin, François Ricordeau, Lucas Marces, Hugo Fornelli, Thierry Petitjean, Amandine Viccica, Elena Charbonnier, Emeric Stauffer, Barbara Charbotel, Jacques Taillard, Renaud Tamisier, Laure Peter‐Derex, Pierre Tankéré   +13 more
wiley   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source