Results 61 to 70 of about 411,191 (267)
Acta Neuropathologica Communications, 2018 Degeneration of noradrenergic locus coeruleus neurons occurs during the prodromal phase of Parkinson’s disease and contributes to a variety of non-motor symptoms, e.g. depression, anxiety and REM sleep behavior disorder.
Martin Timo Henrich +9 more
doaj +1 more source
Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity
Acta Neuropathologica Communications, 2020 The locus coeruleus is the major source of noradrenaline to the brain and contributes to a wide range of physiological and cognitive functions including arousal, attention, autonomic control, and adaptive behaviour.
Sanne Simone Kaalund +6 more
doaj +1 more source
Nature NeuroscienceThe noradrenergic locus coeruleus (LC) regulates arousal levels during wakefulness, but its role in sleep remains unclear. Here, we show in mice that fluctuating LC neuronal activity partitions non-rapid-eye-movement sleep (NREMS) into two brain ...
Alejandro Osorio-Forero +6 more
semanticscholar +1 more source
Nature NeuroscienceNoradrenaline (NA) release from the locus coeruleus (LC) changes activity and connectivity in neuronal networks across the brain, modulating multiple behavioral states. NA release is mediated by both tonic and burst-like LC activity.
Christina Grimm +12 more
semanticscholar +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2020 Abstract Objectives While preliminary evidence suggests that noninvasive vagal nerve stimulation (nVNS) may enhance cognition, to our knowledge, no study has directly assessed the effects of nVNS on brain function and cognitive performance in healthy individuals.
Ruth Klaming +3 more
wiley +1 more source
Locus coeruleus stimulation modulates olfactory bulb evoked potentials [PDF]
, 1987 Field-evoked potentials from the main olfactory bulb in response to stimulation of the olfactory nerve and lateral olfactory tract were measured without and with conditioning stimulation of the locus coeruleus noradrenergic system.
Almli, C. Robert +2 more
core +1 more source
Nature Communications, 2022 Older individuals exhibiting diminished function of the locus coeruleus while learning new information show faster cognitive decline that is typical for Alzheimer’s disease.
Prokopis C. Prokopiou +13 more
doaj +1 more source
The involvement of the locus coeruleus in memory
Behavioral and Neural Biology, 1981 The effects on memory of electrolytic lesions in the locus coeruleus complex (LC) were investigated in three experiments using Swiss mice. Forebrain norepinephrine (NE) levels and histological analysis of lesion sites were used to verify lesion adequacy.
Department of Neuroscience, College of Medicine, University of Florida, Gainesville, Florida 32610, USA ( host institution ) +2 more
openaire +3 more sources
Advanced Science, EarlyView.This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina +6 more
wiley +1 more source
Otorhinolaryngology and Facial Plastic Surgery, 2017 Background: Neurodegeneration in the locus coeruleus (LC) has been documented in several central nervous system (CNS) neurodegenerative diseases and sleep deprivation.
Somaye Mesgar +5 more
doaj +1 more source