Results 61 to 70 of about 380,424 (246)
The Locus Coeruleus in Chronic Pain
International Journal of Molecular SciencesPain perception is the consequence of a complex interplay between activation and inhibition. Noradrenergic pain modulation inhibits nociceptive transmission and pain perception. The main source of norepinephrine (NE) in the central nervous system is the Locus Coeruleus (LC), a small but complex cluster of cells in the pons.
Jorge Castejón España +2 more
openaire +2 more sources
Sensory Neuroscience, EarlyView.Irritable bowel syndrome (IBS) is associated with dysregulation of the autonomic nervous system and altered brain–gut communication. rTMS may alleviate IBS symptoms by modulating central autonomic and pain‐processing networks, potentially restoring sympathovagal balance and reducing visceral hypersensitivity.
Aliasghar Karimi +4 more
wiley +1 more source
Cell Reports, 2018 Summary: How general anesthesia causes loss of consciousness has been a mystery for decades. It is generally thought that arousal-related brain nuclei, including the locus coeruleus (LC), are involved.
Wen-jie Du +9 more
doaj +1 more source
Microinjection of vasopressin into the locus coeruleus of conscious rats
, 1984 To determine whether vasopressin plays a role in central neural control of cardiovascular function by acting on the locus coeruleus we monitored arterial pressure and heart rate responses to graded injections of vasopressin (1-30 ng, 0.1-0.3 microliter ...
Berecek, K. H. +7 more
core +1 more source
Opioid withdrawal syndrome‐associated cognitive impairment: A narrative review
The American Journal on Addictions, EarlyView.Abstract Background and Objectives Opioid withdrawal syndrome (OWS) comprises a transient constellation of subjective symptoms and objective signs expressed by brain and other organs. Although cognitive impairment is well documented in opioid use and addiction, little is known about cognitive impairment that may specifically accompany OWS.
Faizan Khan +2 more
wiley +1 more source
Increased opioid dependence in a mouse model of panic disorder
Frontiers in Behavioral Neuroscience, 2010 Panic disorder is a highly prevalent neuropsychiatric disorder that shows co-occurrence with substance abuse. Here, we demonstrate that TrkC, the high affinity receptor for neurotrophin-3, is a key molecule involved in panic disorder and opiate ...
Xavier Gallego +8 more
doaj +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, EarlyView.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
PREDICT‐PD: A Two‐Stage Approach to Early Identification of Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Sasivimol Virameteekul +9 more
wiley +1 more source
Neuropathology of a patient with Parkinson's disease and biallelic expansion in RFC1
Brain Pathology, EarlyView.This is the first report of neuropathology in biallelic RFC1 expansion‐associated Parkinson’s disease (PD). It shows a synucleinopathy of intraneuronal Lewy bodies consistent with the clinical PD diagnosis while neuropathological CANVAS (Cerebellar Ataxia with Neuropathy and bilateral Vestibular Areflexia) features were absent.
Jussi Sipilä +3 more
wiley +1 more source
Neural Plasticity, 2018 The use of transcranial electrical stimulation (TES) as a method to augment neural activity has increased in popularity in the last decade and a half. The specific application of TES to the left prefrontal cortex has been shown to produce broad cognitive
Matthew S. Sherwood +3 more
doaj +1 more source