Results 51 to 60 of about 380,424 (246)
Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus
Chronic sleep disruption is a risk factor for Alzheimer’s disease (AD), yet mechanisms by which sleep disturbances might promote or exacerbate AD are not understood.
Henry Nick +3 more
doaj +1 more source
Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with variable progression rates that complicate clinical trial design. The data‐driven diffuse malignant (DM), intermediate (IM), and mild‐motor predominant (MMP) subtyping model has prognostic value but lacks disease duration–specific thresholds for prospective use in disease ...
Ahmed Negida +4 more
wiley +1 more source
Our experiments showed that analgesic electroacupuncture (EA: 8c/s, 3V) had a pressor effect in conscious paralysed male rats under artificial respiration.
李慧麟, 周燕春, 顾蕴辉
doaj +2 more sources
Chemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex.
Zafar Iqbal +7 more
doaj +1 more source
Correlations with locus coeruleus (LC).
Correlations with locus coeruleus (LC).
Russell Schachar (760461) +5 more
core +1 more source
Locus coeruleus stimulation modulates olfactory bulb evoked potentials [PDF]
Field-evoked potentials from the main olfactory bulb in response to stimulation of the olfactory nerve and lateral olfactory tract were measured without and with conditioning stimulation of the locus coeruleus noradrenergic system.
Almli, C. Robert +2 more
core +1 more source
Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin +5 more
wiley +1 more source
Apathy in Lewy Body Disorders: A Position Paper
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source
Different Patterns of Locus Coeruleus MRI Alteration in Alzheimer’s and Dementia with Lewy Bodies
Background: The integrity of Locus Coeruleus can be evaluated in vivo using specific Magnetic Resonance Imaging sequences. While this nucleus has been shown to be degenerated both in post-mortem and in vivo studies in Alzheimer’s Disease, for other ...
Fornai F. +16 more
core +1 more source
This review synthesizes epidemiological evidence linking atopic dermatitis to attention‐deficit/hyperactivity disorder in children, proposes an “inflammation‐itch‐neurobehavioral axis” integrating sleep disruption, neuroendocrine dysregulation, and emerging neuro‐immune circuits, and outlines multidisciplinary management strategies targeting both skin ...
Qingyang Zhao +11 more
wiley +1 more source

