Results 51 to 60 of about 411,191 (267)

Locus Coeruleus in Non-Mammalian Vertebrates

Brain Sciences, 2022
The locus coeruleus (LC) is a vertebrate-specific nucleus and the primary source of norepinephrine (NE) in the brain. This nucleus has conserved properties across species: highly homogeneous cell types, a small number of cells but extensive axonal ...
Sijia Wang, Zhirong Wang, Yu Mu
doaj   +1 more source

Correlations with locus coeruleus (LC). [PDF]

, 2019
Correlations with locus coeruleus (LC).
Russell Schachar (760461), Jonathan Lipszyc (6383813), Mehereen Bhaijiwala (6383810), Andre Chevrier (5664088), Simon Graham (760460), Douglas Cheyne (760459)   +5 more
core   +1 more source

Microinjection of vasopressin into the locus coeruleus of conscious rats [PDF]

, 1984
To determine whether vasopressin plays a role in central neural control of cardiovascular function by acting on the locus coeruleus we monitored arterial pressure and heart rate responses to graded injections of vasopressin (1-30 ng, 0.1-0.3 microliter ...
Berecek, K. H., K. G. Hofbauer, H. R. Olpe, R. S. Jones, Jones, R. S., Hofbauer, K. G., K. H. Berecek, Olpe, H. R.   +7 more
core   +1 more source

Combined Optogenetic Approaches Reveal Quantitative Dynamics of Endogenous Noradrenergic Transmission in the Brain

iScience, 2020
Summary: Little is known about the real-time cellular dynamics triggered by endogenous catecholamine release despite their importance in brain functions. To address this issue, we expressed channelrhodopsin in locus coeruleus neurons and protein kinase-A
Shinobu Nomura, Ludovic Tricoire, Ivan Cohen, Bernd Kuhn, Bertrand Lambolez, Régine Hepp   +5 more
doaj   +1 more source

Locus coeruleus-noradrenergic modulation of trigeminal pain: Implications for trigeminal neuralgia and psychiatric comorbidities

Neurobiology of Pain, 2023
Trigeminal neuralgia is the most common neuropathic pain involving the craniofacial region. Due to the complex pathophysiology, it is therapeutically difficult to manage.
Basak Donertas-Ayaz, Robert M. Caudle
doaj   +1 more source

Prefrontal Cortical Connectivity Mediates Locus Coeruleus Noradrenergic Regulation of Inhibitory Control in Older Adults

Journal of Neuroscience, 2021
Response inhibition is a core executive function enabling adaptive behavior in dynamic environments. Human and animal models indicate that inhibitory control and control networks are modulated by noradrenaline, arising from the locus coeruleus.
A. Tomassini, F. Hezemans, R. Ye, K. Tsvetanov, Noham Wolpe, J. Rowe   +5 more
semanticscholar   +1 more source

The effects of footshock and immobilization stress on tyrosine hydroxylase phosphorylation in the rat locus coeruleus and adrenal gland [PDF]

, 2011
Tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis, is regulated acutely by protein phosphorylation. No studies have systematically investigated the time course of TH phosphorylation in vivo in response to different ...
Bobrovskaya, L., L. Guan, Guan, L., L.K. Ong, P.W. Dickson, Dickson, P. W., B. Stutz, Dunkley, P., P.R. Dunkley, Dunkley, P. R., Stutz, B., Ong, L. K., L. Bobrovskaya, Dickson, P., Ong, L.K.   +14 more
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Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep

Science Advances, 2020
Do noises wake you up at night? Blame your locus coeruleus. A defining feature of sleep is reduced responsiveness to external stimuli, but the mechanisms mediating sensory-evoked arousal remain unclear.
Hanna Hayat, Noa Regev, Noa Matosevich, Anna C. Sales, Elena Paredes-Rodriguez, A. Krom, Lottem Bergman, Yong Li, M. Lavigne, E. Kremer, O. Yizhar, A. Pickering, Y. Nir   +12 more
semanticscholar   +1 more source

Organization of the Locus Coeruleus-Norepinephrine System [PDF]

, 2015
The release of the neurotransmitter norepinephrine throughout the mammalian brain is important for modulating attention, arousal, and cognition during many behaviors.
Luo, Liqun, Schwarz, Lindsay A.
core   +1 more source

Less locus coeruleus degeneration and its enhanced influence on neural circuit in Parkinson's tremor

Neurobiology of Disease
Objectives: The involvement of the locus coeruleus in Parkinson's tremor remains unclear. We aimed to decode the role of locus coeruleus in Parkinson's tremor. Methods: We used MRI to examine 120 Parkinson's disease, including 48 tremor-dominant (TD) and
Junyan Sun, Lili Chen, Liang Li, Tao Wu, Tao Feng   +4 more
doaj   +1 more source