Results 31 to 40 of about 380,424 (246)
Locus Coeruleus in Non-Mammalian Vertebrates
Brain Sciences, 2022 The locus coeruleus (LC) is a vertebrate-specific nucleus and the primary source of norepinephrine (NE) in the brain. This nucleus has conserved properties across species: highly homogeneous cell types, a small number of cells but extensive axonal ...
Sijia Wang, Zhirong Wang, Yu Mu
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Neural Plasticity, 2017 The locus coeruleus is connected to the dorsal hippocampus via strong fiber projections. It becomes activated after arousal and novelty, whereupon noradrenaline is released in the hippocampus.
Niels Hansen
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Neurobiology of Pain, 2023 Trigeminal neuralgia is the most common neuropathic pain involving the craniofacial region. Due to the complex pathophysiology, it is therapeutically difficult to manage.
Basak Donertas-Ayaz, Robert M. Caudle
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iScience, 2020 Summary: Little is known about the real-time cellular dynamics triggered by endogenous catecholamine release despite their importance in brain functions. To address this issue, we expressed channelrhodopsin in locus coeruleus neurons and protein kinase-A
Shinobu Nomura +5 more
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Less locus coeruleus degeneration and its enhanced influence on neural circuit in Parkinson's tremor
Neurobiology of DiseaseObjectives: The involvement of the locus coeruleus in Parkinson's tremor remains unclear. We aimed to decode the role of locus coeruleus in Parkinson's tremor. Methods: We used MRI to examine 120 Parkinson's disease, including 48 tremor-dominant (TD) and
Junyan Sun +4 more
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IBRO Neuroscience ReportsBackground: An increasing number of neuroimaging studies have consistently indicated that the locus coeruleus is associated with cognitive impairment in the early stages of Alzheimer's disease, and the locus coeruleus plays a critical role in cognition ...
Liyu Hu +8 more
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Acta Neuropathologica Communications, 2018 Degeneration of noradrenergic locus coeruleus neurons occurs during the prodromal phase of Parkinson’s disease and contributes to a variety of non-motor symptoms, e.g. depression, anxiety and REM sleep behavior disorder.
Martin Timo Henrich +9 more
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Fluid intelligence and the locus coeruleus–norepinephrine system
, 2021 The last decade has seen significant progress identifying genetic and brain differences related to intelligence. However, there remain considerable gaps in our understanding of how cognitive mechanisms that underpin intelligence map onto various brain ...
Tsukahara, Jason S. +3 more
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An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype
Annals of Neurology, EarlyView.Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho +6 more
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, 2022 Previous studies have reported substantial involvement of the noradrenergic system in Parkinson’s disease. Neuromelanin-sensitive MRI sequences and PET tracers have become available to visualize the cell bodies in the locus coeruleus and the density of ...
Kinnerup, Martin B +16 more
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