Results 21 to 30 of about 411,191 (267)
Active control of arousal by a locus coeruleus GABAergic circuit [PDF]
Nature Neuroscience, 2018 Arousal responses linked to locus coeruleus noradrenergic (LC-NA) activity affect cognition. However, the mechanisms that control modes of LC-NA activity remain unknown.
Vincent Breton-Provencher, M. Sur
semanticscholar +2 more sources
Neuroscience and Biobehavioral Reviews, 2023 Memory is essential in defining our identity by guiding behavior based on past experiences. However, aging leads to declining memory, disrupting older adult’s lives.
M. Dahl +3 more
semanticscholar +1 more source
Science Translational Medicine, 2021 Description In vivo and autopsy evidence supports locus coeruleus MRI measures as proxy of initial TAU deposition and amyloid-related memory decline.
H. Jacobs +16 more
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When the Locus Coeruleus Speaks Up in Sleep: Recent Insights, Emerging Perspectives
International Journal of Molecular Sciences, 2022 For decades, numerous seminal studies have built our understanding of the locus coeruleus (LC), the vertebrate brain’s principal noradrenergic system.
Alejandro Osorio-Forero +4 more
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Pupil diameter is not an accurate real-time readout of locus coeruleus activity
eLife, 2022 Pupil diameter is often treated as a noninvasive readout of activity in the locus coeruleus (LC). However, how accurately it can be used to index LC activity is not known.
M. Megemont +2 more
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Frontiers in Psychiatry, 2021 Arousal may be understood on a spectrum, with excessive sleepiness, cognitive dysfunction, and inattention on one side, a wakeful state in the middle, and hypervigilance, panic, and psychosis on the other side.
Jennifer A. Ross, E. V. Van Bockstaele
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The locus coeruleus and central chemosensitivity [PDF]
Respiratory Physiology & Neurobiology, 2010 The locus coeruleus (LC) lies in the dorsal pons and supplies noradrenergic (NA) input to many regions of the brain, including respiratory control areas. The LC may provide tonic input for basal respiratory drive and is involved in central chemosensitivity since focal acidosis of the region stimulates ventilation and ablation reduces CO(2)-induced ...
Gargaglioni, Luciane H. +2 more
openaire +4 more sources
Role of the locus coeruleus and basal forebrain in arousal and attention
Brain Research Bulletin, 2022 Experimental evidence has implicated multiple neurotransmitter systems in either the direct or indirect modulation of cortical arousal and attention circuitry.
Eden B. Maness +5 more
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Acta Neuropathologica, 2021 Alzheimer’s disease (AD) is neuropathologically characterized by the intracellular accumulation of hyperphosphorylated tau and the extracellular deposition of amyloid-β plaques, which affect certain brain regions in a progressive manner.
Billie J. Matchett +3 more
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The Role of the Locus Coeruleus in Pain and Associated Stress-Related Disorders.
Biological Psychiatry, 2021 The locus coeruleus (LC)-noradrenergic system is the main source of noradrenaline in the central nervous system and is involved intensively in modulating pain and stress-related disorders (e.g., major depressive disorder and anxiety) and in their ...
Irene Suárez‐Pereira +5 more
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