Results 11 to 20 of about 31,294 (247)
Locus Coeruleus Optogenetic Modulation: Lessons Learned from Temporal Patterns
Brain Sciences, 2021 After reviewing seminal studies using optogenetics to interrogate the functional role of the locus coeruleus in behavior, we conclude that differences in firing rates and firing patterns of locus coeruleus neurons contribute to locus coeruleus nucleus ...
Carolyn W. Harley, Qi Yuan
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The role of the locus coeruleus in the generation of pathological anxiety
Brain and Neuroscience Advances, 2020 This review aims to synthesise a large pre-clinical and clinical literature related to a hypothesised role of the locus coeruleus norepinephrine system in responses to acute and chronic threat, as well as the emergence of pathological anxiety.
Laurel S Morris +2 more
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Quantifying the contrast of the human locus coeruleus in vivo at 7 Tesla MRI.
PLoS ONE, 2019 The locus coeruleus is a small brainstem nucleus which contains neuromelanin cells and is involved in a number of cognitive functions such as attention, arousal and stress, as well as several neurological and psychiatric disorders.
Klodiana-Daphne Tona +3 more
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Acupuncture-induced changes in locus coeruleus connectivity and memory improvement in patients with amnestic cognitive impairment [PDF]
IBRO Neuroscience ReportsBackground: An increasing number of neuroimaging studies have consistently indicated that the locus coeruleus is associated with cognitive impairment in the early stages of Alzheimer's disease, and the locus coeruleus plays a critical role in cognition ...
Liyu Hu +8 more
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Human narcolepsy is linked to degeneration of both locus coeruleus and hypocretin neurons [PDF]
Nature CommunicationsEarlier studies led to the conclusion that human narcolepsy with cataplexy was correlated with the loss of hypocretin (Hcrt = orexin) neurons in the hypothalamus.
Thomas C. Thannickal +3 more
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Locus coeruleus features are linked to vagus nerve stimulation response in drug-resistant epilepsy [PDF]
Frontiers in NeuroscienceThe locus coeruleus–norepinephrine system is thought to be involved in the clinical effects of vagus nerve stimulation. This system is known to prevent seizure development and induce long-term plastic changes, particularly with the release of ...
Alexandre Berger +20 more
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Neural Plasticity, 2017 The locus coeruleus is connected to the dorsal hippocampus via strong fiber projections. It becomes activated after arousal and novelty, whereupon noradrenaline is released in the hippocampus.
Niels Hansen
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Modulation of physiological reflexes by pain: role of the locus coeruleus
Frontiers in Integrative Neuroscience, 2012 The locus coeruleus is activated by noxious stimuli, and this activation leads to inhibition of perceived pain. As two physiological reflexes, the acoustic startle reflex and the pupillary light reflex, are sensitive to noxious stimuli, this sensitivity,
Elemer eSzabadi
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Locus coeruleus contrast and diffusivity metrics differentially relate to age and memory performance [PDF]
Scientific ReportsNeurocognitive aging researchers are increasingly focused on the locus coeruleus, a neuromodulatory brainstem structure that degrades with age. With this rapid growth, the field will benefit from consensus regarding which magnetic resonance imaging (MRI)
Ilana J. Bennett +5 more
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PLoS ONE, 2023 Patients with Parkinson's disease undergo a loss of melanized neurons in substantia nigra pars compacta and locus coeruleus. Very few studies have assessed substantia nigra pars compacta and locus coeruleus pathology in Parkinson's disease simultaneously
Kristy S Hwang +4 more
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