Quantifying the contrast of the human locus coeruleus in vivo at 7 Tesla MRI. [PDF]
PLoS ONE, 2019 The locus coeruleus is a small brainstem nucleus which contains neuromelanin cells and is involved in a number of cognitive functions such as attention, arousal and stress, as well as several neurological and psychiatric disorders.
Klodiana-Daphne Tona +3 more
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Locus coeruleus features are linked to vagus nerve stimulation response in drug-resistant epilepsy [PDF]
Frontiers in NeuroscienceThe locus coeruleus–norepinephrine system is thought to be involved in the clinical effects of vagus nerve stimulation. This system is known to prevent seizure development and induce long-term plastic changes, particularly with the release of ...
Alexandre Berger +20 more
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Locus Coeruleus magnetic resonance imaging in cognitively intact elderly subjects [PDF]
, 2021 \ua9 2021, The Author(s).The locus coeruleus is the main noradrenergic nucleus of the brain and is often affected in neurodegenerative diseases. Recently, magnetic resonance imaging with specific T1-weighted sequences for neuromelanin has been used to ...
Lombardo F +15 more
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The locus coeruleus and central chemosensitivity [PDF]
Respiratory Physiology & Neurobiology, 2010 The locus coeruleus (LC) lies in the dorsal pons and supplies noradrenergic (NA) input to many regions of the brain, including respiratory control areas. The LC may provide tonic input for basal respiratory drive and is involved in central chemosensitivity since focal acidosis of the region stimulates ventilation and ablation reduces CO(2)-induced ...
Gargaglioni, Luciane H. +2 more
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A possible role of the locus coeruleus in complex regional pain syndrome [PDF]
, 2012 Heightened sensitivity to painful stimulation commonly spreads from the affected limb to the ipsilateral forehead in patients with complex regional pain syndrome (CRPS).
Peter D Drummond +2 more
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Localisation of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress [PDF]
, 2014 The locus coeruleus (LC) nucleus modulates adaptive behavioural responses to stress and dysregulation of LC neuronal activity is implicated in stress-induced mental illnesses.
Metzger, Friedrich +22 more
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A Reciprocal Relationship Between Bottom-up Trace Strength and the Attentional Blink Bottleneck: Relating the LC-NE and ST2 Models [PDF]
, 2008 There is considerable current interest in neural modelling of the attentional blink phenomenon. Two prominent models of this task are the Simultaneous Type Serial Token (ST2) model and the Locus Coeruleus Norepinephrine (LC-NE) model. The former of these
Craston, Patrick +3 more
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, 2021 Previous studies have reported substantial involvement of the noradrenergic system in Parkinson’s disease. Neuromelanin-sensitive MRI sequences and PET tracers have become available to visualize the cell bodies in the locus coeruleus and the density of ...
Kinnerup, Martin B +33 more
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Modulation of physiological reflexes by pain: role of the locus coeruleus
Frontiers in Integrative Neuroscience, 2012 The locus coeruleus is activated by noxious stimuli, and this activation leads to inhibition of perceived pain. As two physiological reflexes, the acoustic startle reflex and the pupillary light reflex, are sensitive to noxious stimuli, this sensitivity,
Elemer eSzabadi
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Locus Coeruleus in Non-Mammalian Vertebrates
Brain Sciences, 2022 The locus coeruleus (LC) is a vertebrate-specific nucleus and the primary source of norepinephrine (NE) in the brain. This nucleus has conserved properties across species: highly homogeneous cell types, a small number of cells but extensive axonal ...
Sijia Wang, Zhirong Wang, Yu Mu
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