Results 41 to 50 of about 31,294 (247)
Different Patterns of Locus Coeruleus MRI Alteration in Alzheimer’s and Dementia with Lewy Bodies
, 2023 Background: The integrity of Locus Coeruleus can be evaluated in vivo using specific Magnetic Resonance Imaging sequences. While this nucleus has been shown to be degenerated both in post-mortem and in vivo studies in Alzheimer’s Disease, for other ...
Fornai F. +16 more
core +1 more source
Locus coeruleus stimulation modulates olfactory bulb evoked potentials [PDF]
, 1987 Field-evoked potentials from the main olfactory bulb in response to stimulation of the olfactory nerve and lateral olfactory tract were measured without and with conditioning stimulation of the locus coeruleus noradrenergic system.
Almli, C. Robert +2 more
core +1 more source
Nature Communications, 2022 Older individuals exhibiting diminished function of the locus coeruleus while learning new information show faster cognitive decline that is typical for Alzheimer’s disease.
Prokopis C. Prokopiou +13 more
doaj +1 more source
The involvement of the locus coeruleus in memory
Behavioral and Neural Biology, 1981 The effects on memory of electrolytic lesions in the locus coeruleus complex (LC) were investigated in three experiments using Swiss mice. Forebrain norepinephrine (NE) levels and histological analysis of lesion sites were used to verify lesion adequacy.
Department of Neuroscience, College of Medicine, University of Florida, Gainesville, Florida 32610, USA ( host institution ) +2 more
openaire +3 more sources
Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke +5 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2020 Abstract Objectives While preliminary evidence suggests that noninvasive vagal nerve stimulation (nVNS) may enhance cognition, to our knowledge, no study has directly assessed the effects of nVNS on brain function and cognitive performance in healthy individuals.
Ruth Klaming +3 more
wiley +1 more source
Tuning arousal with optogenetic modulation of locus coeruleus neurons.
, 2010 Neural activity in the noradrenergic locus coeruleus correlates with periods of wakefulness and arousal. However, it is unclear whether tonic or phasic activity in these neurons is necessary or sufficient to induce transitions between behavioral states ...
de Lecea, Luis +15 more
core +1 more source
Otorhinolaryngology and Facial Plastic Surgery, 2017 Background: Neurodegeneration in the locus coeruleus (LC) has been documented in several central nervous system (CNS) neurodegenerative diseases and sleep deprivation.
Somaye Mesgar +5 more
doaj +1 more source
Advanced Science, EarlyView.This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina +6 more
wiley +1 more source
Molecular Pain, 2017 N-acetylaspartylglutamate (NAAG) is the third most prevalent and widely distributed neurotransmitter in the mammalian nervous system. NAAG activates a group II metabotropic glutamate receptor (mGluR3) and is inactivated by an extracellular enzyme ...
Takahiro Nonaka +6 more
doaj +1 more source