Results 161 to 170 of about 72,586 (301)

Filtering for truth: high-precision taxonomic classification in nanopore shotgun metagenomics data through a KMA-based bioinformatic pipeline (KAPTAIN). [PDF]

BMC Genomics
Van Uffelen A, Gobbo A, Fraiture MA, Posadas A, Roosens NHC, Marchal K, De Keersmaecker SCJ, Vanneste K.   +7 more
europepmc   +1 more source

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities. [PDF]

Cancer Discov
López-Fuentes E, Clugston AS, Lee AG, Sayles LC, Sorensen N, Pons Ventura MV, Leung SG, Dinh T, Breese MR, Sweet-Cordero EA.   +9 more
europepmc   +1 more source

Beyond PBMCs: Polymer‐Based Cell Mimics for Robust TBNK Immunophenotyping Assay Validation

Cytometry Part A, EarlyView.
ABSTRACT Flow cytometry‐based TBNK immunophenotyping is widely used to assess immune status in research, clinical diagnostics, and cell therapy development. Biological control materials such as PBMCs often serve as physiologically relevant controls, but suffer from considerable variability due to donor differences, limited stability, and fluctuations ...
Swetha Pratyusha Gunturu, Subhanip Biswas, Armando Martinez, Brian Kerfs, Kanwal Palla, Louisa D'Lima   +5 more
wiley   +1 more source

Analysis of the Association Between Psychosocial Stressors and Depression Among Family Caregivers of Individuals With Young-Onset Dementia and Late-Onset Dementia: A Cross-Sectional Study. [PDF]

Psychogeriatrics
Maeda Y, Ogata Y, Yumoto Y, Ikeda M.
europepmc   +1 more source

LOD Score [PDF]

, 2019
openaire   +1 more source

In Vivo and In Vitro Evaluation of PTeCA (1H‐Pyrrole‐2,3,4,5‐Tetracarboxylic Acid) in Hair Matrix as a Marker for Oxidative Cosmetic Treatment

Drug Testing and Analysis, EarlyView.
A total of 3378 self‐reported treated and untreated hair samples were analyzed for PTCA and PTeCA by LC‐MS/MS. Moreover, their in vitro formation was assessed in 225 untreated hair by different cosmetic treatments with and without oxidative agents. Data suggest that PTeCA could be a reliable marker for oxidative cosmetic treatments in hair.
Sara Casati, Alessandro Ravelli, Roberta F. Bergamaschi, Agata Magliocco, Sofia Vanerio, Gabriella Roda, Paola Rota, Marica Orioli, Alessio Battistini   +8 more
wiley   +1 more source

Precision of a phage susceptibility spot assay assessed with 154 clinical <i>Staphylococcus aureus</i> isolates. [PDF]

Microbiol Spectr
Herren SC, Zink CL, Mandrekar J, Patel R.   +3 more
europepmc   +1 more source

Chemical Straightening as a Source of Analytical Variability in Hair Testing: A Dual‐Analyte Case Report

Drug Testing and Analysis, EarlyView.
ABSTRACT Hair analysis is increasingly used in forensic toxicology; however, result interpretation may be influenced by cosmetic hair treatments. Although the effects of bleaching, dyeing, and thermal straightening have already been evaluated, data on permanent chemical hair straightening are scarce, particularly under in vivo conditions.
Miriam Blanco‐Ces, Ana de‐Castro‐Ríos, María Cobo‐Golpe, Ángela López‐Rabuñal, Angelines Cruz, Elena Lendoiro   +5 more
wiley   +1 more source

Genetic correlation-guided mega-analysis of DO mice provides mechanistic insight and candidate genes for age-related pathologies. [PDF]

PLoS Genet
Mullis MN, Lefebvre AEYT, Sivasubramanian K, Luo A, Schmid F, Sooknah M, Wright KM, Raj A, Zavala-Solorio J, Zhang C, Riegler J, Gillich A, Ruby JG.   +12 more
europepmc   +1 more source