Abstract Blockchain technology is a digital decentralized data ledger recording transactions in an encrypted format. Its implementation can potentially hold significant advantages for the built environment, particularly in manufacturing and building product usage aligned with Building Information Modeling (BIM). This paradigm shift toward decentralized
Aileen Pfeil +2 more
wiley +1 more source
QTL analysis of <i>Malus baccata</i> 'Jackii'-derived offspring reveals a polygenic inheritance pattern of apple blotch resistance. [PDF]
Pfeifer M +4 more
europepmc +1 more source
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Purification-Driven Modulation of Polyphenol Profile and Protein Glycation-Inhibitory Potential of <i>Actinidia arguta</i> and <i>Actinidia kolomikta</i> Fruit Extracts. [PDF]
Szwengiel A +4 more
europepmc +1 more source
ABSTRACT Aim Persistent high‐risk HPV infection can lead to the development of precancerous lesions, potentially progressing to invasive cancer. HPV status serves not only as a prognostic marker for squamous cell carcinoma (HNSCC) like oropharyngeal squamous cell carcinomas (OPSCC) but also significantly influences clinical management and treatment ...
Min Wang +9 more
wiley +1 more source
Novel Amylin-Based Therapies for Weight Management in Adults With Overweight or Obesity Without Diabetes: A Network Meta-Analysis. [PDF]
Kamrul-Hasan ABM +5 more
europepmc +1 more source
After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis +6 more
wiley +1 more source
Urinary pesticide biomarker associations with depression and anxiety scores from adolescence into young adulthood in the ESPINA cohort. [PDF]
Chronister BNC +10 more
europepmc +1 more source
Investigations Into the Metabolism and Elimination of Tesofensine in Human Urine
This study investigated tesofensine metabolism and urinary elimination after a single 483 μg intake via a dietary supplement. In six volunteers, urine was collected up to 659 h. LC‐HRMS/MS identified four tentative metabolites; maximum urinary concentrations reached 4 ng/mL within 4–48 h.
O. Krug, A. Thomas, M. Thevis
wiley +1 more source
Water soaking in strawberry (Fragaria × ananassa) has a polygenic background and is strongly influenced by environmental factors. [PDF]
Seidler D +4 more
europepmc +1 more source

