Results 151 to 160 of about 1,870,567 (303)

Systematic Study on Phosphatidylethanol (PEth) Stability and De Novo Formation in Authentic Whole Blood Samples

Drug Testing and Analysis, EarlyView.
PEth 16:0/18:1 was stable for at least 5 months when stored at −20°C/−80°C and during non‐temperature controlled postal transport, but PEth 16:0/18:2 showed rapid degradation during transport and at room temperature (RT). Significant Peth 16:0/18:1 de novo formation was observed when stored at −20°C and RT as early as 14 h after sample collection ...
Lana Brockbals, Alina Inderbitzin, Thomas Kraemer, Andrea E. Steuer   +3 more
wiley   +1 more source

Detection of Lower Molecular Mass Peptides, Steroid Esters, and Multi‐Class Substances in a Single Dried Blood Spot for Comprehensive Initial Testing in Doping Control

Drug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled, for the first time, the simultaneous detection of lower molecular mass peptides, steroid esters, and multi‐class menu substances from a single dried blood spot, maximizing analytical coverage while minimizing sample consumption through post‐extraction splitting into two aliquots.
Panagiotis Sakellariou, Andreas Thomas, Jasmin Thelen, Mario Thevis   +3 more
wiley   +1 more source

Caps Off to Abstinence: Unraveling Synthetic Cannabinoid Contamination in Hair Analysis With Headgear Evidence?

Drug Testing and Analysis, EarlyView.
Scalp hair from a subject claiming 2‐year abstinence tested positive for MDMB‐4en‐PINACA and other synthetic cannabinoids. Analysis of the worn baseball cap revealed an identical drug profile, demonstrating external contamination – rather than active use – as the likely source and highlighting a critical pitfall in hair‐based abstinence testing ...
Annette Zschiesche, Yvonne S. Jungel, Detlef Thieme, Laura M. Huppertz, Merja A. Neukamm, Volker Auwärter   +5 more
wiley   +1 more source

Multi‐Cation (High‐Entropy) Doping of Mesoporous Co3O4 Thin Films With Cr, Mn, Fe, Ni, Cu, and Ag: Assessment of the Oxygen Evolution Reaction Performance

EcoEnergy, EarlyView.
Mesoporous Co3O4 thin films doped with Cr, Mn, Fe, Ni, Cu, Ag, and a multi‐cation combination were synthesized via sol‐gel dip‐coating. Structural, optical, and electrochemical analyses reveal Fe and Cu as the most effective dopants for enhancing OER activity, whereas multi‐cation doping shows no synergistic improvement.
Razmik Hansen, Ann‐Kristin Stief, Barbara Gonzalez‐Navarrete, Vipin Kumar, Qingyang Wu, Marcus Einert   +5 more
wiley   +1 more source

Fluorescence Behavior of Water‐Soluble Porphyrins Immobilized on LTA Zeolite and Its Chlorogenic Acid Polyphenol Sensing in Coffee Wastewater

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
During coffee bean and cherry washing, contaminants are released into water, making this process a major source of water pollution. Chlorogenic acid can be efficiently detected using hybrid zeolite–porphyrin materials by measuring fluorescence quenching, achieving detection limits lower than current regulatory thresholds.
João Otávio Donizette Malafatti, Gabriele Magna, Francesco Pizzoli, Fabrizio Caroleo, Cadia D'Ottavi, Williane da Silva Freitas, Ailton José Moreira, Elaine Cristina Paris, Luiz Henrique Capparelli Mattoso, Corrado Di Natale, Roberto Paolesse   +10 more
wiley   +1 more source

Capillary Electrophoresis Methods for the Characterization of Synthetic Nanoparticles

ELECTROPHORESIS, EarlyView.
Capillary electrophoresis (CE) can be applied to evaluate nanoparticle (NP) size, charge, and surface characteristics. Hyphenating CE with ICP‐MS and AF4 can provide comprehensive, multidimensional NP characterization. ABSTRACT Nanoparticles (NPs) exhibit properties distinct from bulk materials of identical chemical composition, with their behavior and
Jordy D. Kruijswijk, Thomas Holmark, Kevin Jooß, Govert W. Somsen   +3 more
wiley   +1 more source

Validation of a High‐Throughput Fluorescent Capillary Electrophoresis Sodium Dodecyl Sulfate Method for Monoclonal Antibody Size Heterogeneity Assessment

ELECTROPHORESIS, EarlyView.
Validation of an LED fluorescence‐based parallel CE‐SDS method for monoclonal antibody size heterogeneity analysis, demonstrating specificity, accuracy, robustness, and precision (RSD < 1%, for monomeric purity and glycosylation). The method provides established UV‐based results while offering greater sensitivity, baseline stability, and substantially ...
Kyle D. Luttgeharm, Manu Grover, Sheng‐Yuan Huang, Whitney A. Pike   +3 more
wiley   +1 more source

Improving the Sensitivity in Chiral Analysis by Capillary Electrophoresis

ELECTROPHORESIS, EarlyView.
Most recent advances for the enhancement of sensitivity in capillary electrophoresis, including off‐line and in‐capillary preconcentration techniques and their combinations, and the use of alternative detection systems to UV–Vis spectrophotometric absorption.
María Castro‐Puyana, Sandra Salido‐Fortuna, María Luisa Marina   +2 more
wiley   +1 more source

Exploring Elimination Profiles and Metabolite Patterns of Brinzolamide and Dorzolamide After Transdermal Exposure for Doping Control Purposes

ELECTROPHORESIS, EarlyView.
Dermal exposure to the carbonic anhydrase inhibitors dorzolamide and brinzolamide is detected in blood and urine using liquid chromatography–high‐resolution/high‐accuracy mass spectrometry. Contamination at milligram level can, therefore, lead to adverse analytical findings in sports drug testing.
Yao Jin, Andreas Thomas, Mario Thevis
wiley   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source