Results 201 to 210 of about 72,001 (287)

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

Small, EarlyView.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk, Rima Nuwayhid, Stefaniya Gaydarova, Eva Bittrich, Natalia Makarova, Susanne Boye, Christo Tzachev, Jan C. Simon, Sandra Franz, Albena Lederer   +9 more
wiley   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Genetic architecture of the murine red blood cell proteome reveals central role of hemoglobin beta cysteine 93 in maintaining redox balance. [PDF]

Cell Genom
Keele GR, Dzieciatkowska M, Hay AM, Vincent M, O'Connor C, Stephenson D, Reisz JA, Nemkov T, Hansen KC, Page GP, Zimring JC, Churchill GA, D'Alessandro A.   +12 more
europepmc   +1 more source

SERS Substrate Fabrication via Rapid Triboelectrification‐Driven Self‐Assembly of Close‐Packed Colloidal Monolayers

Small Methods, EarlyView.
Triboelectrification‐driven self‐assembly of dry colloidal powder offers a promising dry approach to rapidly (<20$<20$ s) attain ordered monolayer colloidal particles for surface‐enhanced Raman spectroscopy applications. ABSTRACT Surface‐enhanced Raman spectroscopy (SERS) amplifies Raman signals on nanostructured metallic surfaces, enabling the ...
Mehdi Feizpour, Ignaas S. M. Jimidar, Mitch T. J. de Waard, Gert Desmet, Heidi Ottevaere   +4 more
wiley   +1 more source

Genetic Basis of Cuticular Hydrocarbon Variation in the Desert Ant <i>Cataglyphis niger</i>. [PDF]

Ecol Evol
Inbar S, Saied B, Cohen P, Frenkel Z, Pellen Y, Korol AB, Privman E.   +6 more
europepmc   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

A Corrected Score Approach for Proportional Hazards Model With Error-Contaminated Covariates Subject to Detection Limits. [PDF]

Stat Med
Song X, Wang CY.
europepmc   +1 more source

Tumour‐informed workflow to use ctDNA as a biomarker for risk of recurrence in head and neck cancer patients post‐treatment

VIEW, EarlyView.
Our study presents a tumour‐informed circulating tumour DNA (ctDNA) workflow designed to enhance the detection of recurrence in head and neck cancer patients, addressing key challenges such as low ctDNA tumour fractions and tumour heterogeneity. Abstract Circulating tumour DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment
Xiaomin Huang, Paul Leo, Mhairi Clout, Lynn Fink, Jonathan Ellis, Brett G. M. Hughes, Lizbeth Kenny, Sarju Vasani, Chamindie Punyadeera   +8 more
wiley   +1 more source

The Ontogeny of Distinct Reproductive Phenotypes in Girls at Risk for PCOS During the Postmenarchal Transition. [PDF]

J Clin Endocrinol Metab
Torchen LC, Aekka A, Brewer K, Sisk R, Ratnam S, Vendrami C, Miller FH, Dunaif A.   +7 more
europepmc   +1 more source

Molecular structure and nickel‐binding capacity of Proteus mirabilis UreE

Acta Crystallographica Section D, EarlyView.
This study presents a 2.0 Å resolution crystal structure and determined the nickel‐binding capacity of the P. mirabilis nickel chaperone UreE. UreE is essential for the delivery of nickel to the metalloenzyme urease, which is key for the ability of P. mirabilis to cause urinary‐tract infections.UreE is a nickel chaperone that is required for the safe ...
Jiayi Pan, Sarah L. Mueller, Nuren Tasneem, Yang Wu, Emily J. Furlong   +4 more
wiley   +1 more source