Results 81 to 90 of about 4,191,932 (286)

Contrast Harmonic-Enhanced Endoscopic Ultrasound (EUS) Is the Perfect Companion of EUS-Guided Tumor Ablation

Gut and Liver, 2020
Serum hepatitis B core-related antigen (HBcrAg) was shown to predict the risk of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients undergoing treatment.
Gianmarco Marocchi, Andrea Lisotti, Pietro Fusaroli   +2 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Association between genetically determined leptin and blood lipids considering alcohol consumption: a Mendelian randomisation study

BMJ Open, 2019
Objectives The objective of this study was to evaluate the association of genetically determined leptin with lipids.Design We conducted a Mendelian randomisation study to assess a potential causal relationship between serum leptin and lipid levels.
Zhiyong Zou, Shengxu Li, Luqi Shen, José F Cordero, Jia-Sheng Wang, Ye Shen, Lirong Liang, Changwei Li   +7 more
doaj   +1 more source

The Clinical Significance and Risk Factors of Colorectal Stricture in Ulcerative Colitis

Gut and Liver, 2020
Serum hepatitis B core-related antigen (HBcrAg) was shown to predict the risk of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients undergoing treatment.
Sung Chul Park, Yoon Tae Jeen
doaj   +1 more source

Distributed Deterministic Edge Coloring using Bounded Neighborhood Independence [PDF]

, 2010
We study the {edge-coloring} problem in the message-passing model of distributed computing. This is one of the most fundamental and well-studied problems in this area.
Barenboim, Leonid, Elkin, Michael
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Consolidated octanol/water partition coefficients: combining multiple estimates from different methods to reduce uncertainties in log K OW

Environmental Sciences Europe
Background The octanol/water partition coefficient (K OW) is a key parameter for assessing the fate and effects of chemicals. It is a metric of their hydrophobicity, related to uptake and accumulation in organisms and specific tissues, and distribution ...
Monika Nendza, Verena Kosfeld, Christian Schlechtriem   +2 more
doaj   +1 more source

Associations of epicardial fat with coronary calcification, insulin resistance, inflammation, and fibroblast growth factor-23 in stage 3-5 chronic kidney disease

BMC Nephrology, 2013
Background Epicardial fat, quantified in a single multi-slice computed tomography (MSCT) slice, is a reliable estimate of total epicardial fat volume (EFV).
Kerr Jasmine D, Holden Rachel M, Morton Alexander R, Nolan Robert L, Hopman Wilma M, Pruss Cynthia M, Garland Jocelyn S   +6 more
doaj   +1 more source

Entecavir Reduced Serum Hepatitis B Core-Related Antigen in Chronic Hepatitis B Patients with Hepatocellular Carcinoma

Gut and Liver, 2020
Serum hepatitis B core-related antigen (HBcrAg) was shown to predict the risk of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients undergoing treatment.
Lung-Yi Mak, Kwan-Lung Ko, Wai-Pan To, Danny Ka-Ho Wong, Wai-Kay Seto, James Fung, Man-Fung Yuen   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source