Results 231 to 240 of about 44,276 (294)

CD4‐Based Chimeric Antigen Receptor (CAR)‐T Cells With Resistance to HIV‐1 Infection and Enhanced Anti‐HIV Efficacy: Covalent Interaction Between CD4‐CAR and HIV‐1 Envelope Glycoprotein

open access: yesJournal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT The current highly active antiretroviral therapy (HAART or ART) effectively suppresses de novo HIV‐1 infection but fails to eliminate HIV reservoir cells, which leads to rapid viral rebound upon ART cessation. Chimeric antigen receptor (CAR) T cells engineered to target HIV‐1 Env⁺ cells offer a promising strategy to eliminate or control these ...
Yaoxian Lou   +9 more
wiley   +1 more source

Charge Regulation and Swelling of Weak Polyelectrolyte Nanogels in Divalent Salt Solutions

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 5, 13 March 2026.
ABSTRACT We use computer simulations to investigate the behavior of a weak polyelectrolyte nanogel in a solution containing divalent salt. In our simulations, we systematically vary the bulk pH value and the bulk concentration of divalent salt, allowing us to study the influence of charge regulation and divalent ions on the ionization behavior, ion ...
David Beyer, Christian Holm
wiley   +1 more source

On the Impact of Artifacts Induced by Mismatches Between Auto‐Calibration Signal and Accelerated 3D GRE Data at 11.7T

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 3, Page 1440-1447, March 2026.
ABSTRACT Purpose The study aims at investigating B0$$ {B}_0 $$ field inhomogeneity artifacts arising from remote locations in the FOV and encountered in accelerated 3D gradient‐recalled echo (GRE) sequences at ultra‐high field, and at providing mitigation strategies.
Joseph Obriot   +8 more
wiley   +1 more source

DREAMER: Rapid and Simultaneous Multiple Contrast Magnetic Resonance Imaging of Solid and Soft Tissue

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 3, Page 1513-1527, March 2026.
ABSTRACT Purpose Pediatric craniofacial imaging may involve examination of both the skull and brain tissues via CT and MRI, respectively. DREAMER (Dual Repetition and Echo Acquisition with Multi‐contrast Encoding and Reconstruction) simultaneously acquires solid‐ and soft‐tissue images, potentially providing a rapid, high‐resolution, and radiation‐free
Brian‐Tinh Duc Vu   +8 more
wiley   +1 more source

Trafficking of the human Na+/H+ antiporter NHA2 to the plasma membrane requires cornichon COPII cargo receptors

open access: yesProtein Science, Volume 35, Issue 3, March 2026.
Abstract A key prerequisite of transporter proteins' function is their trafficking to the target cellular membranes where they fulfill distinct physiological roles. Cornichon proteins (CNIH/Erv14) represent a highly conserved family of coat protein complex II (COPII)‐coated vesicle cargo receptors that facilitate the exit of numerous transporters from ...
Karolína Kacovská   +7 more
wiley   +1 more source

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