Results 31 to 40 of about 1,004,933 (340)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Logicism, Possibilism, and the Logic of Kantian Actualism [PDF]
, 2017 In this extended critical discussion of 'Kant's Modal Metaphysics' by Nicholas Stang (OUP 2016), I focus on one central issue from the first chapter of the book: Stang’s account of Kant’s doctrine that existence is not a real predicate.
Stephenson, Andrew
core
The geometrical basis of arithmetical knowledge: Frege & Dehaene [PDF]
, 2018 Frege writes in Numbers and Arithmetic about kindergarten-numbers and “an a priori mode of cognition” that they may have “a geometrical source.” This resembles recent findings on arithmetical cognition.
Costreie, Sorin
core +3 more sources
Is the Theoretical Unity of the Fallacies Possible?
Informal Logic, 1994 Historically, the fallacies have been neglected as objects of systematic study. Yet, since Hamblin's famous criticism of the state of fallacy theory, a substantial literature has been produced.
John Woods
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
What Kind of Modality Does the Materialist Need For His Supervenience Claim? [PDF]
, 2009 Materialists who do not deny the existence of mental phenomena usually claim that the mental supervenes on the physical, i.e. that there cannot be a change in the mental life of a man without there being a change in the man"s body.
von Wachter, Daniel
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The limits and basis of logical tolerance: Carnap’s combination of Russell and Wittgenstein [PDF]
, 2014 Notes: All data series were filtered by 40-yr Butterworth low-pass filter prior to statistical analysis. Differencing:△no difference,α1stdifference.
David D. Zhang (585964) +3 more
core +4 more sources
Frege on the Foundation of Geometry in Intuition
Journal for the History of Analytical Philosophy, 2015 I investigate the role of geometric intuition in Frege’s early mathemat- ical works and the significance of his view of the role of intuition in geometry to properly understanding the aims of his logicist project.
Jeremy Shipley
doaj +1 more source