Results 41 to 50 of about 250,917 (320)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Zhang Dongsun’s Encounters with “Logicism”

Asian Studies
The article surveys the early work of Zhang Dongsun on topics like logicism of Bertrand Russell and scientific philosophy, which aimed to criticise its foundations and replace them with a Neo-Kantian alternative. It tries to show how a series of Zhang’s
Jan VRHOVSKI
doaj   +1 more source

Carnap’s Principle of Tolerance and logical pluralism [PDF]

, 2015
Logical pluralism is the claim that there is more than one adequate logic. Many authors consider Carnap as one of the forerunners of logical pluralism.
Dias, Diogo
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The geometrical basis of arithmetical knowledge: Frege & Dehaene [PDF]

, 2018
Frege writes in Numbers and Arithmetic about kindergarten-numbers and “an a priori mode of cognition” that they may have “a geometrical source.” This resembles recent findings on arithmetical cognition.
Costreie, Sorin
core   +3 more sources

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez, Pinar Ozge Avar‐Aydin, Kelly Rogers, Daniel J. Lovell, Jennifer Huggins, Alexei Grom, Hermine I. Brunner, Grant S. Schulert, Sheila T. Angeles‐Han, Mekibib Altaye, Amy Cassedy, Arthur B. Meyers, Tracy V. Ting   +12 more
wiley   +1 more source

Logicism Revisited

Principia: An International Journal of Epistemology, 2001
In this paper, I develop a new defense of logicism: one that combines logicism and nominalism. First, I defend the logicist approach from recent criticisms; in particular from the charge that a crucial principle in the logicist reconstruction of ...
Otávio Bueno
doaj  

Frege on the Foundation of Geometry in Intuition

Journal for the History of Analytical Philosophy, 2015
I investigate the role of geometric intuition in Frege’s early mathemat- ical works and the significance of his view of the role of intuition in geometry to properly understanding the aims of his logicist project.
Jeremy Shipley
doaj   +1 more source

Arnošt Kolman’s Critique of Mathematical Fetishism [PDF]

, 2020
Arnošt Kolman (1892–1979) was a Czech mathematician, philosopher and Communist official. In this paper, we would like to look at Kolman’s arguments against logical positivism which revolve around the notion of the fetishization of mathematics.
Mácha, Jakub, Zouhar, Jan
core   +1 more source

Identification of storm eye from Satellite image data using fuzzy logic with machine learning [PDF]

, 2022
Monu Yadav, Laxmi Narayan Das
openalex   +1 more source