Results 41 to 50 of about 761 (264)
, 2017 Since their inception, the Perspectives in Logic and Lecture Notes in Logic series have published seminal works by leading logicians. Many of the original books in the series have been unavailable for years, but they are now in print once again. Logicism,
Paul C. Gilmore
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Logical Nihilism and the Logic of ‘prem’
Logic and Logical Philosophy, 2020 As the final component of a chain of reasoning intended to take us all the way to logical nihilism, Russell (2018) presents the atomic sentence ‘prem’ which is supposed to be true when featuring as premise in an argument and false when featuring as conclusion in an argument. Such a sentence requires a non-reflexive logic and an endnote by Russell (2018)
openaire +4 more sources
Is the Theoretical Unity of the Fallacies Possible?
Informal Logic, 1994 Historically, the fallacies have been neglected as objects of systematic study. Yet, since Hamblin's famous criticism of the state of fallacy theory, a substantial literature has been produced.
John Woods
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Zhang Dongsun’s Encounters with “Logicism”
Asian StudiesThe article surveys the early work of Zhang Dongsun on topics like logicism of Bertrand Russell and scientific philosophy, which aimed to criticise its foundations and replace them with a Neo-Kantian alternative. It tries to show how a series of Zhang’s
Jan VRHOVSKI
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Fuzzy logics as the logics of chains
Fuzzy Sets and Systems, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Libor Behounek, Petr Cintula
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source