Results 31 to 40 of about 1,091 (205)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Mass media e rubriche linguistiche. "Linguaccia mia", Linkiesta.it, di Maurizio Assalto tra regole, norme, errori ed etimo sincronico e/o diacronico

open access: yesLingue e culture dei media, 2022
Si analizza la rubrica linguistica "LINGUACCIA MIA", pubblicata settimanalmente ogni lunedì dal gennaio 2002 su Linkiesta.it, dal giornalista Maurizio Assalto, di cui si evidenzia la ideologia oscillante tra descrittivismo (in solo due testi su 25 ...
Salvatore Claudio Sgroi
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Russell's Logicism [PDF]

open access: yes, 2018
Bertrand Russell was one of the best-known proponents of logicism: the theory that mathematics reduces to, or is an extension of, logic. Russell argued for this thesis in his 1903 The Principles of Mathematics and attempted to demonstrate it formally in ...
Klement, Kevin C.
core   +2 more sources

Zhang Dongsun’s Encounters with “Logicism”

open access: yesAsian Studies
The article surveys the early work of Zhang Dongsun on topics like logicism of Bertrand Russell and scientific philosophy, which aimed to criticise its foundations and replace them with a Neo-Kantian alternative. It tries to show how a series of Zhang’s
Jan VRHOVSKI
doaj   +1 more source

Is the Theoretical Unity of the Fallacies Possible?

open access: yesInformal Logic, 1994
Historically, the fallacies have been neglected as objects of systematic study. Yet, since Hamblin's famous criticism of the state of fallacy theory, a substantial literature has been produced.
John Woods
doaj   +1 more source

Logicism Renewed

open access: yes, 2017
Since their inception, the Perspectives in Logic and Lecture Notes in Logic series have published seminal works by leading logicians. Many of the original books in the series have been unavailable for years, but they are now in print once again. Logicism,
Paul C. Gilmore
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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