Results 71 to 80 of about 160,535 (299)
The case report focuses on Cognitive Behavioural Guided Therapy of obsessive‑compulsive symptomatology in a boy with autism and other neurodevelopmental disorders in comorbidity.
Lenka Vacková
doaj +1 more source
Impact of foods with health logo on ssaturated fat, sodium and sugar intake of young Dutch adults [PDF]
Objective Health logos are introduced to distinguish foods with ‘healthier’ nutrient composition from regular foods. In the present study, we evaluated the effects of changed food compositions according to health logo criteria on the intake of saturated ...
Bulder, A. +8 more
core +1 more source
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic +21 more
wiley +1 more source
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo +6 more
wiley +1 more source
Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao +12 more
wiley +1 more source
Logos founder and editor emeritus Gordon Graham reflects on his nearly two-decade love affair with this journal which he launched in 1990. After a long and distinguished career in publishing—including from 1974 to 1990 as chairman and chief executive of Butterworths, the legal and scientific publisher that has been a division of Reed International ...
openaire +2 more sources
A one‐pot, aqueous, and scalable method for synthesizing chiral lanthanide supramolecular emitters using terbium and threonine is reported. The aqueous solution of these chiral emitters displays the following features: (i) 100 % transparency, (ii) tunable luminescence and CPL, and (iii) a pH feedback loop that controls the “on‐off” states of ...
P. M. Ajay Sekhar +5 more
wiley +1 more source
Nature provides a timely opportunity in the fall to glimpse some of its mathematical and scientific wonders, hidden in the multi-colored carpet that showers and blankets the earth. Trees and leaves can be commanded--in Logo of course.
Harris, Judi
core +1 more source
The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells
Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato +9 more
wiley +1 more source
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai +4 more
wiley +1 more source

