Results 81 to 90 of about 29,799 (243)

A phase IIb randomized, chronic-dosing, incomplete block, cross-over study of glycopyrronium, delivered via metered dose inhaler, compared with a placebo and an active control in patients with moderate-to-severe COPD

Respiratory Research, 2018
Background Long-acting muscarinic antagonist (LAMA) and long-acting β2-agonist (LABA) bronchodilators are key to the pharmacologic treatment of chronic obstructive pulmonary disease (COPD).
Edward M. Kerwin, Selwyn Spangenthal, Christine Kollar, Earl St Rose, Colin Reisner   +4 more
doaj   +1 more source

Down-titration from high-dose combination therapy in asthma: Removal of long-acting β2-agonist

, 2010
SummaryBackgroundAsthma guidelines recommend reducing inhaled corticosteroids (ICS) to the minimum effective dose, but the timing of long-acting β2-agonist (LABA) withdrawal is unclear.
Wark, Peter A.B., Sand, Ingrid B., Reddel, Helen K., Peters, Matthew J., Gibson, Peter G., Hoyos, Camilla M., Jenkins, Christine R.   +6 more
core   +1 more source

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal, Emily Moon, Georgios Kallikas   +2 more
wiley   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Long-acting β2-agonists: how are they used in an optimal way?

, 1997
Inhaled long-acting β2-agonists are frequently used for the treatment of asthma. When introduced to the market, the drug was accompanied by a debate among physicians and scientists raising warnings against the use of β2-agonists, leading to a risk of ...
Larsson, L., Bjermer, L.
core   +1 more source

Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort

Movement Disorders, EarlyView.
Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard, Agnès Fournier, Émeline Courtois, Fanny Artaud, Pascale Tubert‐Bitter, Emmanuel Roze, Ismaïl Ahmed, Anne C.M. Thiébaut, Alexis Elbaz, Thi Thu Ha Nguyen   +9 more
wiley   +1 more source

Trade Unions and Sustainability: An Integrative Review

Sustainable Development, EarlyView.
ABSTRACT Despite the growing presence of trade unions (TUs) in sustainability discussions, academic research on their role is still scattered. This article presents an integrative review of 110 peer‐reviewed English‐language academic articles on this topic, indexed in Scopus and Web of Science and published between 1997 and early 2025.
Branko Bembič, Urša Golob, Klement Podnar   +2 more
wiley   +1 more source

Effect of Procaterol, a β2 Selective Adrenergic Receptor Agonist, on Airway Inflammation and Hyperresponsiveness

Allergology International, 2007
Background: β-agonists are frequently used as bronchodilators for asthma as not only a reliever but also a controller, and their utility has increased with the development of long-acting β2 selective drugs.
Hiroyuki Tashimo, Naomi Yamashita, Hirofumi Ishida, Hiroyuki Nagase, Tetsuya Adachi, Junichi Nakano, Koichi Yamamura, Tomoko Yano, Hisanao Yoshihara, Ken Ohta   +9 more
doaj   +1 more source

Assessing physiological, behavioral and movement responses to Suprelorin implant delivery methods in free‐ranging eastern grey kangaroos Macropus giganteus

Wildlife Biology, EarlyView.
Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva, Sebastien Comte, Tamara Keeley, Maquel Brandimarti, Catherine A. Herbert   +4 more
wiley   +1 more source

Effect of monitoring adherence to regular inhaled corticosteroid (ICS) alone or in combination with a long-acting β2-agonist (LABA) using electronic methods on asthma outcomes: a narrative systematic review. [PDF]

BMJ Open, 2023
Almutairi M, Marriott JF, Mansur A.
europepmc   +1 more source