Results 61 to 70 of about 6,876,355 (238)

Simulation modeling: an illustrative method to estimate drug clinical and economic effectiveness (retrospective meta-analysis of anti-asthmatic therapy in children in a hospital setting)

Сеченовский вестник, 2017
The article presents an assessment of the clinical, economic and clinical-economic components of the basic anti-asthmatic therapy regimens in children in hospital setting.
O. V. Zhukova
doaj  

Adherence to inhaled corticosteroids and long-acting β2-agonists in asthma: A MASK-air study

Pulmonology
Introduction Adherence to controller medication is a major problem in asthma management, being difficult to assess and tackle. mHealth apps can be used to assess adherence.
B. Sousa-Pinto, R. Louis, J.M. Anto, R. Amaral, A. Sá-Sousa, W. Czarlewski, L. Brussino, G.W. Canonica, C. Chaves Loureiro, A.A. Cruz, B. Gemicioglu, T. Haahtela, M. Kupczyk, V. Kvedariene, D.E. Larenas-Linnemann, Y. Okamoto, M. Ollert, O. Pfaar, N. Pham-Thi, F. Puggioni, F.S. Regateiro, J. Romantowski, J. Sastre, N. Scichilone, L. Taborda-Barata, M.T. Ventura, I. Agache, A. Bedbrook, S. Becker, K.C. Bergmann, S. Bosnic-Anticevich, M. Bonini, L.-P. Boulet, G. Brusselle, R. Buhl, L. Cecchi, D. Charpin, F. de Blay, S. Del Giacco, J.C. Ivancevich, M. Jutel, L. Klimek, H. Kraxner, P. Kuna, D. Laune, M. Makela, M. Morais-Almeida, R. Nadif, M. Niedoszytko, N.G. Papadopoulos, A. Papi, V. Patella, B. Pétré, D. Rivero Yeverino, C. Robalo Cordeiro, N. Roche, P.W. Rouadi, B. Samolinski, M. Savouré, M.H. Shamji, A. Sheikh, C. Suppli Ulrik, O.S. Usmani, A. Valiulis, A. Yorgancioglu, T. Zuberbier, J.A. Fonseca, E.M. Costa, J. Bousquet   +68 more
doaj   +1 more source

Long-acting beta2-agonists for chronic obstructive pulmonary disease. [PDF]

, 2013
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up.
Walters, JA, Chris Mavergames, Kew, KM, Mavergames, C, Kayleigh M Kew, Julia AE Walters   +5 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Effect of Bronchodilator and Steroid Use on Heart Disease and Stroke Risks in a Bronchiectasis–Chronic Obstructive Pulmonary Disease Overlap Cohort: A Propensity Score Matching Study

Frontiers in Pharmacology, 2019
Background: To determine the effects of bronchodilator, steroid, and anti-arrhythmia drug use on the risk of heart disease/stroke (HDS) in patients with bronchiectasis–chronic obstructive pulmonary disease overlap syndrome (BCOS).Methods: We ...
Jun-Jun Yeh, Jun-Jun Yeh, Jun-Jun Yeh, Yu-Cih Yang, Yu-Cih Yang, Chung Y. Hsu, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao   +9 more
doaj   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Long acting β2-adrenocepter agonists are not associated with atrial arrhythmias after pulmonary resection

, 2017
Background Long-acting β2-adrenoceptor agonists have been shown to increase the risk of atrial arrhythmias in patients with stable chronic obstructive pulmonary disease.
Cheng-long Huang, Keiji Yamanashi, Toshiro Katayama, Tsuyoshi Shoji, Satoshi Marumo, Motonari Fukui, Ryota Sumitomo   +6 more
core   +1 more source

Model‐Informed Approaches for Pediatric Type 2 Diabetes Evidence Generation: Insights from a Model‐Based Longitudinal HbA1c Meta‐Analysis from EMA Marketing Authorization Applications

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence generation for antihyperglycemic therapies in pediatric type 2 diabetes mellitus (T2DM) remains challenging, with most randomized trials failing to demonstrate statistically significant reductions in glycated hemoglobin (HbA1c), partly due to substantial between‐subject variability.
Pieter J. Colin, Efthymios Manolis, Jeroen V. Koomen   +2 more
wiley   +1 more source

Therapeutic approaches of asthma and COPD overlap

Allergology International, 2018
Asthma and COPD overlap (ACO) is an important clinical phenotype, due to the low-health-related quality of life (QOL), rapid decline in lung function, frequent exacerbation, and high economic burden.
Mitsuko Kondo, Jun Tamaoki
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source