Results 121 to 130 of about 126,067 (267)

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source

Future perspectives of anticholinergics for the treatment of asthma in adults and children

, 2019
Roland Buhl,1 Eckard Hamelmann2,3 1Pulmonary Department, Johannes Gutenberg University Hospital Mainz, Mainz, Germany; 2Children’s Center Bethel, Evangelic Hospital Bethel, Department of Pediatrics, Bielefeld, Germany; 3University Children’s
Buhl R, Hamelmann E
core  

Impact of TCAs and Gabapentin on Saliva and BMI in Adults With Xerostomia

Journal of Oral Rehabilitation, EarlyView.
In adults with medication‐related xerostomia, tricyclic antidepressant and gabapentin use were not independently associated with BMI or oral dryness after adjustment. Instead, female sex, anticholinergic burden, obstructive sleep apnea, GERD, thyroid disease, depression and race demonstrated stronger associations with reduced salivary flow and greater ...
Waldir Martineli Filho, Andre Pedroso, Alhanoof Khaled Alarfaj, Karina Dutra Pinto Pereira, Abdul Basir Barmak, Szilvia Arany   +5 more
wiley   +1 more source

The effective treatment of COPD: Anticholinergics and what else?

, 2006
Long-acting bronchodilator therapy should be considered when a COPD patient is symptomatic. For patients whose conditions are not sufficiently controlled by monotherapy, combining medications of different classes seems a convenient treatment for ...
CAZZOLA, MARIO, Matera M. G., Cazzola M., Matera M.G.   +2 more
core   +1 more source

Intravesical Botox: An Effective Therapy for Refractory Monosymptomatic Nocturnal Enuresis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Monosymptomatic nocturnal enuresis (MNE) significantly impacts many children, with substantial patient groups refractory to conventional first‐line treatments. Intravesical Botox is used for various refractory functional voiding disorders in children, but its efficacy in MNE has not been widely established.
Eliza Szwarcberg, Chris Kimber, Kiarash Taghavi   +2 more
wiley   +1 more source

Factors associated with low adherence to inhaled therapy in patients with chronic respiratory diseases: a cross-sectional study

BMC Pulmonary Medicine
Background Because of their high prevalence, chronic respiratory diseases, like asthma and chronic obstructive pulmonary disease, represent main public health problems. They are mainly treated through inhaled therapy.
Esther Ribes Murillo, Josep Ramon Marsal Mora, Marta Micol Bachiller, Leonardo Galván Santiago, Núria Nadal Braqué, Marta Ortega Bravo   +5 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Antagonism of pro-2-PAM using central and peripheral anticholinergic drugs

, 2011
(M.A.) -- Towson University, 2011.The goal of this study was two-fold. Experiment 1 characterized the intoxicating tremor produced by two known tremor-inducing drugs, oxotremorine and physostigmine in order to characterize the tremoregenic effects of a ...
Ferrara, Teresa M.
core   +1 more source

Pharmacokinetics of Intramuscular and Intravenous Glycopyrrolate in Juvenile New Zealand White Rabbits

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Glycopyrrolate is an alternative to atropine to treat bradyarrhythmias in anesthetized rabbits; however, there are no pharmacokinetic studies in the literature. Six female New Zealand White rabbits received glycopyrrolate 0.05 mg/kg intravenously (IV) in the cephalic vein or intramuscularly (IM) in a complete crossover design.
Jocelyn Marchiori, Andrea Sanchez, Kristen Messenger, Jennifer M. Reinhart, Hugues Beaufrère, Sonja Fonfara, Alexander Valverde, Yu Gu, Ron Johnson   +8 more
wiley   +1 more source

Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study

Oral Diseases, EarlyView.
ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai, Gil Caspi, Akhilanand Chaurasia, Gavriel Chaushu, Daya Masri, Ehud Jonas   +5 more
wiley   +1 more source