Results 141 to 150 of about 126,067 (267)

Impedance‐Controlled Multipoint Radiofrequency Ablation for Chronic Rhinitis: A Randomized Controlled Trial

International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 553-560, June 2026.
ABSTRACT Background The purpose of this randomized controlled trial (RCT) was to demonstrate that posterior nasal nerve ablation treatment with the NEUROMARK System is superior to a sham control procedure in patients with chronic rhinitis. Methods In this prospective, multicenter, single‐blinded, superiority RCT, 132 participants were randomized 2:1 to
Masayoshi Takashima, Randall A. Ow, Richard D. Thrasher, Ellen M. O'Malley, William R. Blythe, Omar G. Ahmed   +5 more
wiley   +1 more source

Comparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis

International Journal of COPD, 2018
Mohamed Ismail Abdul Aziz,1,* Ling Eng Tan,1,* David Bin-Chia Wu,1 Fiona Pearce,1 Gerald Seng Wee Chua,2 Liang Lin,1 Ping-Tee Tan,1 Kwong Ng1 1Agency for Care Effectiveness, Ministry of Health, Singapore; 2Division of Medicine, Ng Teng Fong General ...
Abdul Aziz MI, Tan LE, Wu DB, Pearce F, Chua GSW, Lin L, Tan PT, Ng K   +7 more
doaj  

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1706-1715, June 2026.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung, Ju Hwan Kim, Da Eun Hyeon, Jeongmoon Ji, Min Young Lee, Hayun Choi, Dong Yun Lee, Min Woo Kim, Yoonmin Jang, Seonghoon Hwang, Jaehyeong Cho, Seok Young Song, Sang Youl Rhee, Jae Myung Cha, Won‐Woo Seo, Chang‐Won Jeong, Seung‐Jin Kwag, Woo Jin Kim, Jaeuk Hwang, Min‐ho Kim, Rae Woong Park, Ju‐Young Shin   +21 more
wiley   +1 more source

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

Brain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence, Daniel Fulton, Poppy Brown, Subashini Suresh, Mark Morris, Paraskevi Goggolidou, Sree Chaithanya, Marcus Abbawy, Amelia Wild, Prashant Nasa, Niharika A. Duggal, Fang Gao‐Smith, Zubair Ahmed, Suresh Renukappa, Tonny Veenith   +14 more
wiley   +1 more source

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi‐Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death

Clinical Cardiology, Volume 49, Issue 6, June 2026.
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam, Mohammad Hosein Yazdanpanah, Narges Fereydouni   +2 more
wiley   +1 more source

Progress of Immunotherapies in Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Parkinson's disease (PD) is caused by an immune disorder triggered by α‐synuclein, leading to a persistent neuroinflammatory cycle that drives the disease from non‐motor symptoms to the motor stage. Second, it presents active and passive immunotherapy strategies targeting α‐synuclein and their potential in slowing down the disease progression.
Yong Peng, Xu‐hui Kang, Shun‐yu Yao, Xiuli Zhang, Sugimoto Kazuo, Jia Liu, Miao‐qiao Du, Lan‐xin Lin, Dai‐yi Jiang, Quan Chen, Hong Jin   +10 more
wiley   +1 more source

Effect of repeated Waon therapy on exercise tolerance and pulmonary function in patients with chronic obstructive pulmonary disease: a pilot controlled clinical trial

International Journal of COPD, 2013
Hiroshi Kikuchi,1,2 Nobuyoshi Shiozawa,1 Shingo Takata,1 Kozo Ashida,1 Fumihiro Mitsunobu11Division of Medicine, Misasa Medical Center, Okayama University Hospital, Misasa, Tottori, Japan; 2Division of Internal Medicine, Takamatsu Hospital KKR, Takamatsu,
Kikuchi H, Shiozawa N, Takata S, Ashida K, Mitsunobu F   +4 more
doaj  

Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review systematically explores exercise as a multi‐target intervention for RBD, highlighting its mechanisms of action and regulatory effects on key pathophysiological processes. ABSTRACT Backgrounds REM sleep behavior disorder (RBD) is a prodromal non‐motor symptom of Parkinson's disease (PD) and other α‐synucleinopathies, affecting approximately ...
Xinhui Qiu, Zihui Wang, Ruixue Xu, Yiying Hu, Weidong Le   +4 more
wiley   +1 more source

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

Association Between Psychiatrists' Subjective Clinical Behavior Scores and Objective Quality Indicators Based on Discharge Prescriptions: A Nationwide Multicenter Study Based on the EGUIDE Project

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Association between quality indicators and clinical behaviors related to the guidelines for schizophrenia. ABSTRACT Aim Psychiatrists often perceive their clinical practices as guideline‐concordant; however, discrepancies frequently exist between perceived and actual prescribing behaviors.
Kazuhiko Yamamuro, Naomi Hasegawa, Yusuke Arai, Hikaru Hori, Hiroyuki Muraoka, Toru Horinouchi, Naoki Hashimoto, Shinichiro Ochi, Takashi Tsuboi, Hirotaka Yamagata, Junya Matsumoto, Satsuki Ito, Toshiaki Onitsuka, Kazutaka Ohi, Hisashi Yamada, Jun‐ichi Iga, Ken Inada, Koichiro Watanabe, Norio Yasui‐Furukori, Ryota Hashimoto   +19 more
wiley   +1 more source