Results 161 to 170 of about 126,067 (267)

Fentanyl Compromises Lower‐Airway Mechanics and Naloxone Triggers a Transient Mechanical Overshoot

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the leading cause of death following opioid overdose, due to its effects on central rhythm generation, and airway and thoracic constriction. While the effects on rhythm generation have been well documented, the effects of fentanyl on airway constriction are less well understood. We tested the
Riley R. Parks, Marissa J. Andersen, Mackenna L. Hatfield, Madeline M. Johnson, Nicholas J. Burgraff   +4 more
wiley   +1 more source

Mirabegron for overactive bladder. [PDF]

Can Fam Physician
Falk J, Lane J, Kim T, Chan K.
europepmc   +1 more source

Evaluation of a Pharmacist‐Led Intervention Focused on the Deprescribing of Cardiovascular and Antidiabetic Medication in Older Patients With Polypharmacy: Patients' and Pharmacists' Experiences

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 6, June 2026.
ABSTRACT Background In the Netherlands, community pharmacists (CPs) are required to conduct annual clinical medication reviews (CMRs) for older patients with polypharmacy. In practice, these reviews are insufficiently implemented, and opportunities to deprescribe inappropriate cardiovascular and antidiabetic medications are often missed.
Jamila Abou, Petra J. M. Elders, Rob van Marum, Jacqueline Hugtenburg   +3 more
wiley   +1 more source

Increased mortality in dementia patients using inhaled anticholinergics: A nationwide register study from the Swedish registry on dementia/cognitive disorders, SveDem. [PDF]

J Alzheimers Dis
Al-Mayahi S, Andersson ML, Mo M, Garcia-Ptacek S, Xu H, Wikström E, Eriksdotter M.   +6 more
europepmc   +1 more source

Nonlinear Associations Between Frailty and Medication Burden in Hospitalized Older Adults

Geriatrics &Gerontology International, Volume 26, Issue 6, June 2026.
Medication burden in hospitalized older adults—including total medications, potentially inappropriate medications, and anticholinergic burden—showed nonlinear associations with frailty, peaking at moderate frailty (CFS 5–6) before attenuating in advanced frailty.
Hiroyuki Umegaki, Hirotaka Nakashima, Fumihiko Mizokami, Yosuke Yamada, Kazuhisa Watanabe, Chisato Fujisawa, Hitoshi Komiya, Tomihiko Tajima, Shosuke Satake, Yasushi Takeya, Mitsutaka Yakabe   +10 more
wiley   +1 more source

A Multicentre, 4-Year Mirror-Image Study Comparing the Effectiveness of Long-Acting Injectable Antipsychotics in the Treatment of Bipolar Disorder: Results From the LAICO Study. [PDF]

Bipolar Disord
García-Carmona JA, Barnett J, Campos-Navarro MP, Mason K, Simal-Aguado J, Pappa S.   +5 more
europepmc   +1 more source

Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu, Yue Sun, Kexin Chen, Jieyi Wang, Bingcheng Lu, Hongqiang Xie, Xiaoming Liu, Cong Huang, Xingling Jian, Bo Yu   +9 more
wiley   +1 more source

Rates and Predictors of Persistent LUTS Medication Use After Laser Enucleation of the Prostate. [PDF]

Low Urin Tract Symptoms
Filzmayer M, Traumann MI, Humke C, Müller MJ, Mandel PC, Kluth LA, Becker A, Chun FK, Kosiba M.   +8 more
europepmc   +1 more source

[Practice guideline 'Medical treatment of COPD']

, 2008
Contains fulltext : 69288.pdf (Publisher’s version ) (Closed access)The practice guideline 'Medical treatment of COPD' completes the practice guideline for diagnostics and non-medicinal treatment.
Tuut, M.K., Grol, M.H., Broeders, M.E.A.C., Dekhuijzen, P.N.R.   +3 more
core  

Migraine and Restless Legs Syndrome: A Meta‐Analysis

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio, Maria Cropano, Giada Panzino, Mariachiara Gaita, Giulio Cicarelli, Piero Barbanti, Gerardo Casucci, Simona Raimo, Antonio Costanzo   +8 more
wiley   +1 more source