Results 91 to 100 of about 13,121 (228)

Management of Paediatric Acute Asthma in a Metropolitan Emergency Department: A Retrospective Audit

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To evaluate adherence to the Sydney Children's Hospital Network (SCHN) Asthma‐Acute Management Practice Guideline in the management of paediatric patients presenting to a metropolitan emergency department (ED). Methods A cross‐sectional retrospective audit of 153 paediatric ED presentations with acute asthma between March 2023 and February
Yasmine Toufaili, Nounu Sarukkali
wiley   +1 more source

Maintenance therapy in COPD: time to phase out ICS and switch to the new LAMA/LABA inhalers?

open access: yesInternational Journal of COPD, 2017
Syed Mohammad Tariq,1 Enson C Thomas2 1Department of Respiratory Medicine, Luton and Dunstable University Hospital, Luton, 2Respiratory Unit, Bedford Hospital, Bedford, UK Abstract: Long-term maintenance therapy for COPD is evolving rapidly.
Tariq SM, Thomas EC
doaj  

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

open access: yesTransfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa   +20 more
wiley   +1 more source

Long-acting muscarinic antagonist use in adults with asthma: real-life prescribing and outcomes of add-on therapy with tiotropium bromide

open access: yes, 2015
David Price,1,2 Alan Kaplan,3 Rupert Jones,4 Daryl Freeman,5 Anne Burden,2 Shuna Gould,2 Julie von Ziegenweidt,2 Muzammil Ali,2 Christine King,2 Mike Thomas6 1Academic Centre of Primary Care, University of Aberdeen, Aberdeen, 2Research in Real-Life ...
Burden A   +9 more
core  

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Current appraisal of single inhaler triple therapy in COPD

open access: yesInternational Journal of COPD, 2018
Brian Lipworth, Chris RuiWen Kuo, Sunny Jabbal Division of Molecular & Clinical Medicine, Scottish Centre for Respiratory Research, Ninewells Hospital and Medical School, University of Dundee, Scotland, UK Abstract: A single inhaler containing ...
Lipworth B, Kuo CRW, Jabbal S
doaj  

Table_S3_28Aug2019 – Supplemental material for Systematic review and network meta-analysis of the efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler in comparison with other long-acting muscarinic antagonist/long-acting β2-agonist fixed-dose combinations in COPD

open access: yes, 2019
Supplemental material, Table_S3_28Aug2019 for Systematic review and network meta-analysis of the efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler in comparison with other long-acting muscarinic antagonist/long-acting β2 ...
Patrick Darken (3584720)   +6 more
core   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Positioning new pharmacotherapies for COPD

open access: yesInternational Journal of COPD, 2015
Igor Z Barjaktarevic,1 Anthony F Arredondo,1 Christopher B Cooper1,2 1Department of Medicine, 2Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA Abstract: COPD imposes ...
Barjaktarevic IZ   +2 more
doaj  

Figure_S1 – Supplemental material for Systematic review and network meta-analysis of the efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler in comparison with other long-acting muscarinic antagonist/long-acting β2-agonist fixed-dose combinations in COPD

open access: yes, 2019
Supplemental material, Figure_S1 for Systematic review and network meta-analysis of the efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler in comparison with other long-acting muscarinic antagonist/long-acting β2-agonist fixed-
Patrick Darken (3584720)   +6 more
core   +1 more source

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